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Histomorphological study of the bone regeneration capacity of platelet-richplasma, bone marrow and tricalcium phosphate Experimental study on pigs
Chimenos-Küstner, Eduardo; López-López, Jose; Manzanares-Céspedes, Cristina; Muñoz-Sánchez, Juan; Castañeda-Vega, Pol; Jané-Salas, Enrique; Álvarez-López, Jose-Manuel; Gimeno-Sanding, Alvaro.
Afiliação
  • Chimenos-Küstner, Eduardo; University of Barcelona. Department of Dentistry. Full Professor of Oral Medicine. Barcelona. Spain
  • López-López, Jose; University of Barcelona. Department of Dentistry. Full Professor of Oral Medicine. Barcelona. Spain
  • Manzanares-Céspedes, Cristina; University of Barcelona. Faculty of Dentistry. Full Professor of Anatomy. Barcelona. Spain
  • Muñoz-Sánchez, Juan; Bellvitge Health Sciences Campus. Assistant Doctor of Hematology. University of Barcelona. Barcelona. Spain
  • Castañeda-Vega, Pol; University of Barcelona. Faculty of Dentistry. Dentist. Masters in Oral Medicine. Barcelona. Spain
  • Jané-Salas, Enrique; University of Barcelona. Faculty of Dentistry. Associate Professor of Oral Medicine. Barcelona. Spain
  • Álvarez-López, Jose-Manuel; Autonomous University of Barcelona. Full Professor of Computing. Image and Sound Engineer. Barcelona. Spain
  • Gimeno-Sanding, Alvaro; University of Barcelona. Head of the Animal Facility at Bellvitge Health Sciences Campus. Veterinarian. Barcelona. Spain
Med. oral patol. oral cir. bucal (Internet) ; 14(12): 620-627, dic. 2009. ilus, tab
Artigo em Inglês | IBECS | ID: ibc-78746
Biblioteca responsável: ES1.1
Localização: BNCS
ABSTRACT

Introduction:

Bone defects are rather common after oral surgery and may prove difficult to repair.

Objective:

Weprovide a histomorphological analysis of the bone regenerative capacity of platelet-rich plasma at different concentrationsand the extraction of platelet-rich bone marrow, compared with &bgr;-tricalcium phosphate.

Methodology:

We performed an experimental study on 8 pigs, in which we performed trepanations of the mandible inorder to place the materials to be studied. Using an electron microscope, we observed the samples obtained andtook a series of photographs in order to analyze the samples through a gray-scale histogram system.

Results:

Ossification phenomena were present in 96% of the charged defects, regardless of the material used to fillit. Platelet-rich plasma (PRP) and the bone marrow (M) showed an equivalent degree of osteogenesis, 12.3 and 13.4respectively, which is greater in than the control group. The platelet-poor plasma (PPP) shows a capacity similarto the control groups (C), with an average count of 14.03 and 14.12 respectively. Tricalcium phosphate (TP) wasshown to be effective as an ossification inducer, 3.03 times stronger than the control group.

Conclusions:

Ossificationoccurs in most of the charged defects. PRP and M had the greatest osteogenic capacity but PPP was nomore effective than the control (AU)
RESUMEN
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Coleções: Bases de dados nacionais / Espanha Base de dados: IBECS Assunto principal: Materiais Biocompatíveis / Medula Óssea / Regeneração Óssea / Fosfatos de Cálcio / Plasma Rico em Plaquetas / Mandíbula Limite: Animais Idioma: Inglês Revista: Med. oral patol. oral cir. bucal (Internet) Ano de publicação: 2009 Tipo de documento: Artigo Instituição/País de afiliação: Autonomous University of Barcelona/Spain / Bellvitge Health Sciences Campus/Spain / University of Barcelona/Spain
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Coleções: Bases de dados nacionais / Espanha Base de dados: IBECS Assunto principal: Materiais Biocompatíveis / Medula Óssea / Regeneração Óssea / Fosfatos de Cálcio / Plasma Rico em Plaquetas / Mandíbula Limite: Animais Idioma: Inglês Revista: Med. oral patol. oral cir. bucal (Internet) Ano de publicação: 2009 Tipo de documento: Artigo Instituição/País de afiliação: Autonomous University of Barcelona/Spain / Bellvitge Health Sciences Campus/Spain / University of Barcelona/Spain
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