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The relationship of ocular geometry with refractive error in normal and low birth weight adults
Fiebeta, Achim; Nickels, Stefan; Schulz, Andreas; Münzel, Thomas; Wild, Philipp S; Beutel, Manfred E; Urschitz, Michael S; Lackner, Karl J; Pfeiffer, Norbert; Schuster, Alexander K.
Afiliação
  • Fiebeta, Achim; University Medical Center of the Johannes Gutenberg-University Mainz. Department of Ophthalmology. Mainz. Germany
  • Nickels, Stefan; University Medical Center of the Johannes Gutenberg-University Mainz. Department of Ophthalmology. Mainz. Germany
  • Schulz, Andreas; University Medical Center of the Johannes Gutenberg-University Mainz. Center for Cardiology. Preventive Cardiology and Preventive Medicine. Mainz. Germany
  • Münzel, Thomas; University Medical Center of the Johannes Gutenberg-University Mainz. Center for Cardiology-Cardiology I. Mainz. Germany
  • Wild, Philipp S; University Medical Center of the Johannes Gutenberg-University Mainz. Center for Thrombosis and Hemostasis (CTH). Mainz. Germany
  • Beutel, Manfred E; University Medical Center of the Johannes Gutenberg University Mainz. Department of Psychosomatic Medicine and Psychotherapy. Mainz. Germany
  • Urschitz, Michael S; University Medical Center of the Johannes Gutenberg-University Mainz. Institute of Medical Biostatistics, Epidemiology and Informatics (IMBEI). Mainz. Germany
  • Lackner, Karl J; University Medical Center of the Johannes Gutenberg-University Mainz. Institute of Clinical Chemistry and Laboratory Medicine. Mainz. Germany
  • Pfeiffer, Norbert; University Medical Center of the Johannes Gutenberg-University Mainz. Department of Ophthalmology. Mainz. Germany
  • Schuster, Alexander K; University Medical Center of the Johannes Gutenberg-University Mainz. Department of Ophthalmology. Mainz. Germany
J. optom. (Internet) ; 14(1): 50-57, ene.-mar. 2021. tab, graf
Artigo em Inglês | IBECS | ID: ibc-200292
Biblioteca responsável: ES1.1
Localização: BNCS
ABSTRACT

PURPOSE:

Low birth weight (BW) individuals have an increased risk for myopic refractive error. However, it is unclear which ocular geometric alterations lead to an increase in myopic refractive error. This study aims to evaluate the impact of ocular biometry in interaction with BW on refractive error.

METHODS:

Participants of the prospective, observational, population-based Gutenberg Health Study (GHS) with self-reported BW aged 40-80 years and objective refraction and optical biometry were included. Linear regression analyses were conducted to evaluate associations between spherical equivalent with corneal power, anterior chamber depth, lens thickness and axial length and its interaction with BW adjusted for age and sex. Low BW was defined as BW < 2500 g and normal BW between 2500-4000 g.

RESULTS:

Overall, 5123 participants were included. Linear regression showed an interaction of axial length (B = 0.009/100 g, p = 0.002) with BW on spherical equivalent while corneal power, anterior chamber depth and lens thickness revealed no interaction with BW on refractive error. Furthermore, linear regression analysis revealed, that axial length explains 58% of variance of spherical equivalent in low BW subjects, and 54% in normal BW subjects. In contrast, corneal power explained 1% of variance of spherical equivalent in both groups.

CONCLUSIONS:

Our results indicate that axial length variation explains the majority of variance in refractive error, while steeper corneal shape has no conclusive effects on refractive error. Low BW is not linked to effects of steeper corneal shape on myopic refractive error, while the effect of axial length on myopia is fractionally enlarged in those

subjects:

RESUMEN
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Assuntos

Texto completo: Disponível Coleções: Bases de dados nacionais / Espanha Base de dados: IBECS Assunto principal: Recém-Nascido de Baixo Peso / Miopia Limite: Adulto / Idoso / Feminino / Humanos / Masculino / Recém-Nascido Idioma: Inglês Revista: J. optom. (Internet) Ano de publicação: 2021 Tipo de documento: Artigo Instituição/País de afiliação: University Medical Center of the Johannes Gutenberg University Mainz/Germany / University Medical Center of the Johannes Gutenberg-University Mainz/Germany

Texto completo: Disponível Coleções: Bases de dados nacionais / Espanha Base de dados: IBECS Assunto principal: Recém-Nascido de Baixo Peso / Miopia Limite: Adulto / Idoso / Feminino / Humanos / Masculino / Recém-Nascido Idioma: Inglês Revista: J. optom. (Internet) Ano de publicação: 2021 Tipo de documento: Artigo Instituição/País de afiliação: University Medical Center of the Johannes Gutenberg University Mainz/Germany / University Medical Center of the Johannes Gutenberg-University Mainz/Germany
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