Peritumorous lymph-vascular invasion, grade of histologic differentiation, and myometrial infiltration as prognostic factors of endometrial carcinoma

RESUMO

The authors evaluated 50 patients with endometrial carcinoma studying the prognostic parameters histologic grade, myometrial invasion and lymph-vascular space invasion. The patients were divided into two groups A - a good prognosis group (33 cases) - with no recurrence and/or metastasis occuring for five years; and B - a bad prognosis group (17 cases) - with recurrence and/or metastasis or death within five years. We concluded that lymph-vascular space invasion was more frequent in group B, and was a reliable parameter for vad prognosis. The lymph-vascular space invasion was always accompained by myometrial invasion and patients whose myometrium had not been involved did not have lymph-vascular space invasion. In both groups, in well-differentiated tumors, there was no lymph-vascular space involvement. The well-differentiated tumors were statistically more frequent in the good prognosis group. Myometrial invasion was not statistically significant as a prognostic parameter