Structural features of LPPG and related compounds isolated from Trypanosoma cruzi trypomastigotes
Braz. j. med. biol. res
; 27(2): 227-31, Feb. 1994. ilus
Artigo
em Inglês
| LILACS
| ID: lil-138289
Biblioteca responsável:
BR26.1
RESUMO
A hydrophobic fraction isolated from trypomastigotes of Trypanosoma cruzi is being characterized using immunological and chemical techniques. The lipopeptidophosphoglycan (LPPG) was identified in this fraction since it gave a positive reaction with anti-LPPG rabbit serum and had similar structural features such as the presence of ceramide as the lipid moiety, furanoic galactose, and a glycan moiety consistent with that obtained from an authentic sample of epimastigote LPPG, as judged by thin-layer chromatography. Furthermore, the hydrophobic fraction contained other glycolipids with different structural features. The lipid moiety of these compounds is alkylglycerol rather than a ceramide, the carbohydrate chain appears to be less complex than that in LPPG and no reactivity was observed towards an anti-LPPG serum
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Coleções:
Bases de dados internacionais
Base de dados:
LILACS
Assunto principal:
Fosfolipídeos
/
Trypanosoma cruzi
/
Glicoconjugados
/
Peptidoglicano
Limite:
Animais
Idioma:
Inglês
Revista:
Braz. j. med. biol. res
Assunto da revista:
Biologia
/
Medicina
Ano de publicação:
1994
Tipo de documento:
Artigo
/
Congresso e conferência