Sorodiagnóstico da Doença de Chagas: novo reagente para o teste de hemaglutinaçäo indireta (THAIIAL) / Chagas' disease serological diagnosis: a new reagent to the indirect hemagglutination test (IHATIAL)
Rev. Soc. Bras. Med. Trop
; 29(2): 137-44, Mar.-Apr. 1996. ilus, graf, tab
Artigo
em Português
| LILACS, Sec. Est. Saúde SP
| ID: lil-187140
Biblioteca responsável:
BR1.1
RESUMO
A new reagent was designed to the indirect hemagglutination test (IHATIAL), utilizing goose red blood cells as inert matrix and standardized for the field diagnosis of American trypanosomiasis. The objective was to substitute the lyophilized or frozen reagent of IHAT produced routinely using human erythrocytes in the Adolfo Lutz Institute (Säo Paulo/Brazil). The standardized reagent presented a long stability in liquid suspension, and was evaluated in 137 serum samples from patient with and without Chagas' disease, by IHATIAL. The diagnostic performance of this test was similar to the IHAT utilizing human erythrocytes and to that of a commercial IHAT kit. The sensitivity was 1.00, specificity 0.98, predictive value of positive 0.96 and of negative 1.00. Different batches of reagent successively produced proved to be reproducible in a quality control method. The new reagent is more economic than the former reagent, it can be produced easily and may be applicable to the seroepidemiologic studies.
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Coleções:
Bases de dados nacionais
/
Brasil
Contexto em Saúde:
ODS3 - Saúde e Bem-Estar
/
Doenças Negligenciadas
Problema de saúde:
Meta 3.3: Acabar com as doenças tropicais negligenciadas e combater as doenças transmissíveis
/
Doença de Chagas
/
Doenças Negligenciadas
Base de dados:
LILACS
/
Sec. Est. Saúde SP
Assunto principal:
Testes de Hemaglutinação
/
Doença de Chagas
/
Gansos
Tipo de estudo:
Estudo diagnóstico
/
Estudo prognóstico
Limite:
Animais
/
Humanos
Idioma:
Português
Revista:
Rev. Soc. Bras. Med. Trop
Ano de publicação:
1996
Tipo de documento:
Artigo