Imunodiagnóstico da esquistossomose mansônica com baixa carga parasitária / Immunodiagnosis of schistosomiasis mansonsi with light worm burden
Rev. Soc. Bras. Med. Trop
; 29(2): 145-52, Mar.-Apr. 1996. ilus, tab
Artigo
em Português
| LILACS, Sec. Est. Saúde SP
| ID: lil-187141
Biblioteca responsável:
BR1.1
ABSTRACT
Presently, the schistosomiasis mansoni with low worm burden is frequent, thus immunologic assays of interest for the field diagnosis of Schistosoma mansoni light infections were evaluated here. Assays not assessed before (group I) and those requiring better validation (group II) for the screening of light infections were included in this study. In the group I, the immunofluorescence assays for the detection of IgM antibodies to worm antigens (IgM IFAw) and IgG antibodies to egg antigens (IgG IFAe) gave high levels of sensitivity, specificity, efficiency and predictive value of positive. However, the immunoenzymatic assays for the detection of IgM antibodies to worm antigens (IgM ELISAw) and to egg antigens (IgM ELISAe) had lower levels than the former assays. The assays from the group II designed mostly for the detection of IgG antibodies to same parasite antigens showed good diagnostic performance. The data obtained here contributed to evidenciate at least three category of immunoassays, and we concluded that those from the category I are suitable for seroepidemiologic purposes by keeping their diagnostic features unchanged even varying significantly the intensity of S. mansoni infection.
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Coleções:
Bases de dados nacionais
/
Brasil
Contexto em Saúde:
Doenças Negligenciadas
Problema de saúde:
Helmintíase
/
Doenças Negligenciadas
/
Esquistossomose
/
Zoonoses
Base de dados:
LILACS
/
Sec. Est. Saúde SP
Assunto principal:
Schistosoma mansoni
/
Esquistossomose mansoni
/
Imunoglobulina G
/
Imunoglobulina M
/
Anticorpos Anti-Helmínticos
/
Fezes
Tipo de estudo:
Estudo prognóstico
Limite:
Animais
/
Humanos
Idioma:
Português
Revista:
Rev. Soc. Bras. Med. Trop
Ano de publicação:
1996
Tipo de documento:
Artigo