Demencia subcortical en paraparesia espástica tropical asociada a HTLV-I: estudio de 43 casos / Subcortical dementia in HTLV-I tropical spastic paraparesis: study of 43 cases
Rev. méd. Chile
; 127(4): 444-50, abr. 1999. tab, graf
Article
em Es
| LILACS
| ID: lil-243915
Biblioteca responsável:
CL1.1
RESUMO
Background:
Central nervous system damage associated to HTLV-I does not limit itself to the spinal cord, but also involves subcortical structures, producing cognitive impairment and behavioral changes which eventually could conform a new form of subcortical dementia.Aim:
To study cognitive changes in patients with HTLV-I associated myelopathy. Patients andmethods:
Forty three patients (31 female) with Tropical Spastic Paraparesis, aged 52 years old as a mean and with a disease lasting a mean of 7.5 years, were studied. The diagnosis was based on clinical, radiological and neurophysiological changes. The virus was identified with ELISA, indirect immunofluorecence, Western Blot or proviral DNA identification. Cognitive assessment was done using the Wechler Adult Intelligence Scale (WAIS) and Benton Visual Retention Test (form D). Patients were grouped according to their motor disability in; 23 patients with independent spastic gait, 11 patients that needed support to walk and 9 patients unable to walk.Results:
WAIS test demonstrated cognitive impairment with special deficit in some subtests such as Digit Span, Digit Symbol, Picture Arrangement and Object Assembly. Benton Test also disclosed cognitive impairment. There was a positive relationship between cognitive and motor performance.Conclusions:
At least 50 percent of patients with Tropical Spastic Paraparesis have certain degree of intellectual and affective impairment
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Coleções:
01-internacional
Base de dados:
LILACS
Assunto principal:
Paraparesia Espástica Tropical
/
Demência
Tipo de estudo:
Etiology_studies
Limite:
Female
/
Humans
/
Male
Idioma:
Es
Revista:
Rev. méd. Chile
Assunto da revista:
MEDICINA
Ano de publicação:
1999
Tipo de documento:
Article