The role of xanthine oxidase and the effects of antioxidants in ischemia reperfusion cell injury
Acta physiol. pharmacol. ther. latinoam
; 49(1): 13-20, 1999. tab
Artigo
em Inglês
| LILACS
| ID: lil-245928
Biblioteca responsável:
BR1.1
RESUMO
During last years considerable interest has been devoted to understand the role of oxugen radicals in the inschemia induced cell injury associated with reperfusion. In the brain and in others tissues, free radicals play a role as modulators of vascular tone as well as a cytotoxic role as part of the ischemia associated pathology. This review discusses methods for free radical detection in brain and in other tissues, mechanisms of radical production in the course of the ischemia reperfusion process, and the efficacy of potential antioxidant agents in post ischemia therapy, especially with respect to allopurinol, an inhibitor of xanthine oxidase, and the role of taurine and its derivatives as antioxidants in different organs including the brain.
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Coleções:
Bases de dados internacionais
Base de dados:
LILACS
Assunto principal:
Xantina Oxidase
/
Niacinato de Xantinol
/
Traumatismo por Reperfusão
/
Inibidores Enzimáticos
/
Isquemia
/
Antioxidantes
Idioma:
Inglês
Revista:
Acta physiol. pharmacol. ther. latinoam
Assunto da revista:
Farmacologia
/
Fisiologia
/
Terapêutica
Ano de publicação:
1999
Tipo de documento:
Artigo