Serum cytokine levels in autoimmune and non-autoimmune hyperthyroid states
Braz. j. med. biol. res
; 33(1): 65-9, Jan. 2000.
Artigo
em Inglês
| LILACS
| ID: lil-252258
Biblioteca responsável:
BR1.1
ABSTRACT
Although the role of interleukin-2 (IL-2) and interferon gamma (yIFN) is still poorly understood in hyperthyroid diseases, it is reasonable to assume that these cytokines may be present at higher levels in Graves' disease (GD) than in other primarily non-autoimmune thyroid diseases. In order to look for an easy method to distinguish GD from primarily non-autoimmune causes of hyperthyroidism, we compared 13 healthy individuals with 21 treated and untreated hyperthyroid GD patients and with 19 patients with hyperthyroidism due to other etiologies 7 cases of multinodular goiter, 5 cases of excessive hormone replacement and 7 cases of amiodarone-associated hyperthyroidism. All patients presented low TSH levels and a dubious clinical thyroid state. We found a good correlation between TSH and serum IL-2 levels (r = 0.56; P
Texto completo:
Disponível
Coleções:
Bases de dados internacionais
Base de dados:
LILACS
Assunto principal:
Tireotropina
/
Doença de Graves
/
Citocinas
/
Interferon gama
/
Interleucina-2
/
Hipertireoidismo
Tipo de estudo:
Estudo diagnóstico
/
Estudo de etiologia
Limite:
Adolescente
/
Adulto
/
Criança
/
Feminino
/
Humanos
Idioma:
Inglês
Revista:
Braz. j. med. biol. res
Assunto da revista:
Biologia
/
Medicina
Ano de publicação:
2000
Tipo de documento:
Artigo