Protective immunity induced by a Yersinia enterocolitica serovar 0: 8 cellular extract
Biocell
; 20(3): 235-241, Dec. 1996.
Artigo
em Inglês
| LILACS
| ID: lil-335995
Biblioteca responsável:
BR1.1
ABSTRACT
The purpose of this study was to investigate the protective power of a cellular extract (CE) from Y. enterocolitica 08 grown in condition of expression of chromosomal antigens. Mice were immunized by s.c. route and challenged with 0 LD50 (1 x 10(4) CFU/ml). Immunoblotting showed that CE-specific serum reacted with several CE antigens. Prominent bands, of molecular weights 60 and 35.5, were present in cytoplasmic and membrane fraction, respectively. The lipopolysaccharide (LPS) was detected in CE. These findings suggest that chromosomally-encoded antigens present in CE may induce protection against Y. enterocolitica infection. Both humoral and cellular immune response contribute to protection in mice.
Buscar no Google
Coleções:
Bases de dados internacionais
Contexto em Saúde:
ODS3 - Saúde e Bem-Estar
/
Doenças Negligenciadas
Problema de saúde:
Meta 3.3: Acabar com as doenças tropicais negligenciadas e combater as doenças transmissíveis
/
Doenças Negligenciadas
/
Zoonoses
Base de dados:
LILACS
Assunto principal:
Yersinia enterocolitica
/
Antígenos de Bactérias
Limite:
Animais
Idioma:
Inglês
Revista:
Biocell
Assunto da revista:
Clulas
Ano de publicação:
1996
Tipo de documento:
Artigo
País de afiliação:
Argentina
Instituição/País de afiliação:
Universidad Nacional de Córdoba/AR
/
Universidad Nacional de San Luis/AR