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Evolution of patients with squamous cell carcinoma of upper aerodigestive tract
Amar, Ali; Franzi, Sergio Altino; Rapoport, Abräo.
Afiliação
  • Amar, Ali; Hospital Heliópolis. Departamento de Cirurgia da Cabeça e Pescoço e Otorrinolaringologia. Säo Paulo. BR
  • Franzi, Sergio Altino; Hospital Heliópolis. Departamento de Cirurgia da Cabeça e Pescoço e Otorrinolaringologia. Säo Paulo. BR
  • Rapoport, Abräo; Hospital Heliópolis. Departamento de Cirurgia da Cabeça e Pescoço e Otorrinolaringologia. Säo Paulo. BR
São Paulo med. j ; 121(4): 155-158, July 1, 2003. tab, graf
Artigo em Inglês | LILACS | ID: lil-348721
Biblioteca responsável: BR1.1
RESUMO
CONTEXT Local and regional recurrences are frequent in patients with squamous cell carcinoma of the upper aerodigestive tract and early diagnosis is important for salvage treatment.

OBJECTIVE:

To identify the period of highest risk for the development of recurrences after surgical treatment of squamous cell carcinoma of the upper aerodigestive tract, in spite of radical therapy, in order to plan the follow-up for these patients. TYPE OF STUDY Cross-sectional, descriptive.

SETTING:

Department of Head and Neck Surgery/Otorhinolaryngology, Heliópolis Hospital (Hosphel), Säo Paulo, Brazil.

PARTICIPANTS:

A review was made of the hospital records of 889 patients with squamous cell carcinoma of the upper aerodigestive tract surgically treated between October 1977 and December 1996 364 had oral cavity tumors, 107 had tumors of the oropharynx, 152 of the hypopharynx and 266, larynx tumors. The disease was stage I in 14 patients, stage II in 117, stage III in 352, stage IV in 397 and 9 patients were not staged. MAIN MEASUREMENTS The interval between treatment and recurrence of disease was evaluated. The results were expressed as medians, quartiles (25 percent to 75 percent) and percentiles (10 percent to 90 percent). The annual incidence of recurrences and second tumors was calculated.

RESULTS:

Seventy-four percent of the recurrences were diagnosed within 18 months post-treatment. The local and regional recurrences and distant metastases showed medians of 270, 210 and 435 postoperative days respectively. The incidence of a second primary tumor varied from 2 to 3.1 percent a year.

CONCLUSION:

The majority of recurrences occurred within 18 months after the initial surgical treatment. The incidence of a second tumor remained stable after the first post-treatment year
Assuntos
Texto completo: Disponível Coleções: Bases de dados internacionais Base de dados: LILACS Assunto principal: Carcinoma de Células Escamosas / Neoplasias de Cabeça e Pescoço / Processos Neoplásicos Tipo de estudo: Estudo observacional / Estudo prognóstico / Fatores de risco / Estudo de rastreamento Limite: Humanos Idioma: Inglês Revista: São Paulo med. j Assunto da revista: Cirurgia Geral / Ciˆncia / Ginecologia / Medicina / Medicina Interna / Obstetr¡cia / Pediatria / Sa£de Mental / Sa£de P£blica Ano de publicação: 2003 Tipo de documento: Artigo País de afiliação: Brasil Instituição/País de afiliação: Hospital Heliópolis/BR
Texto completo: Disponível Coleções: Bases de dados internacionais Base de dados: LILACS Assunto principal: Carcinoma de Células Escamosas / Neoplasias de Cabeça e Pescoço / Processos Neoplásicos Tipo de estudo: Estudo observacional / Estudo prognóstico / Fatores de risco / Estudo de rastreamento Limite: Humanos Idioma: Inglês Revista: São Paulo med. j Assunto da revista: Cirurgia Geral / Ciˆncia / Ginecologia / Medicina / Medicina Interna / Obstetr¡cia / Pediatria / Sa£de Mental / Sa£de P£blica Ano de publicação: 2003 Tipo de documento: Artigo País de afiliação: Brasil Instituição/País de afiliação: Hospital Heliópolis/BR
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