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Urolithiasis associated with topiramate
Eggener, Scott; Kim, Samuel C; User, Herbert M; Pazona, Joseph; Nadler, Robert B; Preminger, Glenn M.
Afiliação
  • Eggener, Scott; Northwestern University Medical School. Department of Urology. Chicago. US
  • Kim, Samuel C; Northwestern University Medical School. Department of Urology. Chicago. US
  • User, Herbert M; Northwestern University Medical School. Department of Urology. Chicago. US
  • Pazona, Joseph; Northwestern University Medical School. Department of Urology. Chicago. US
  • Nadler, Robert B; Northwestern University Medical School. Department of Urology. Chicago. US
  • Preminger, Glenn M; Duke University Medical Center. Division of Urology Surgery. Durham. US
Int. braz. j. urol ; 30(1): 29-31, Jan.-Feb. 2004. ilus
Artigo em Inglês | LILACS | ID: lil-359781
Biblioteca responsável: BR1.1
RESUMO

OBJECTIVE:

Topiramate is a sulfamate-substituted monosaccharide anticonvulsant used as adjunctive therapy for intractable refractory seizures. It is report a case of topiramate-induced urolithiasis. CASE REPORT A 35-year-old man presented with acute, right-sided, colicky flank pain. He denied hematuria or dysuria. He was in use of phenytoin, risperidone, phenobarbital, and topiramate. The total daily dose of topiramate was 375 mg. A CT scan showed a 7 x 1 mm curvilinear density at the right ureterovesical junction with proximal hydrouretronephrosis. He was managed with rigid ureteroscopic stone extraction and the calculus metabolic analysis revealed the stone was composed of carbonate apatite (70 percent), calcium oxalate dihydrate (20 percent), and calcium oxalate monohydrate (10 percent).

COMMENTS:

The present case typifies many features of topiramate-induced urolithiasis. Those who care for patients with urinary stone disease should be aware of this association.
Assuntos
Texto completo: Disponível Coleções: Bases de dados internacionais Base de dados: LILACS Assunto principal: Cálculos Urinários / Frutose / Anticonvulsivantes Tipo de estudo: Relato de casos Limite: Adulto / Humanos / Masculino Idioma: Inglês Revista: Int. braz. j. urol Assunto da revista: Urologia Ano de publicação: 2004 Tipo de documento: Artigo País de afiliação: Estados Unidos Instituição/País de afiliação: Duke University Medical Center/US / Northwestern University Medical School/US

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Texto completo: Disponível Coleções: Bases de dados internacionais Base de dados: LILACS Assunto principal: Cálculos Urinários / Frutose / Anticonvulsivantes Tipo de estudo: Relato de casos Limite: Adulto / Humanos / Masculino Idioma: Inglês Revista: Int. braz. j. urol Assunto da revista: Urologia Ano de publicação: 2004 Tipo de documento: Artigo País de afiliação: Estados Unidos Instituição/País de afiliação: Duke University Medical Center/US / Northwestern University Medical School/US
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