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Effect of fibrin glue derived from snake venom on the viability of autogenous split-thickness skin graft
Rahal, S. C; Amaral, M. S. P; Pai, V. D; Barravieira, S. R. C. S; Caporali, E. H. G; Crocci, A. J.
Afiliação
  • Rahal, S. C; UNESP. Faculty of Veterinary Medicine and Animal Science. Department of Veterinary Surgery and Anesthesiology. Botucatu. BR
  • Amaral, M. S. P; UNOESTE. Faculty of Agrarian Science. Presidente Prudente. BR
  • Pai, V. D; UNOESTE. Faculty of Agrarian Science. Presidente Prudente. BR
  • Barravieira, S. R. C. S; UNESP. Faculty of Medicine. Department of Dermatology. Botucatu. BR
  • Caporali, E. H. G; UNESP. Faculty of Veterinary Medicine and Animal Science. Department of Veterinary Surgery and Anesthesiology. Botucatu. BR
  • Crocci, A. J; UNESP. Bioscience Institute. Department of Biostatistics. São Paulo. BR
J. venom. anim. toxins incl. trop. dis ; 10(2): 161-172, 2004. ilus, tab
Artigo em Inglês | LILACS | ID: lil-363349
Biblioteca responsável: BR33.1
ABSTRACT
The aim of this study was to analyze the effect of snake venom derived from fibrin glue on the viability of split-thickness skin graft. Nine crossbreed dogs were used. Full-thickness skin segments measuring 4X4 cm were bilaterally excised from the proximal radial area on each dog. A split-thickness skin graft was harvested from left lateral thoracic area using a freehand graft knife, and was secured to the left recipient bed using several simple interrupted sutures of 3-o nylon (sutured graft). A split-thickness skin graft was harvested from the right lateral thoracic area using a graft knife. Fibrin glue derived from snake venom was applied to the recipient bed, and 8 equidistant simple interrupted sutures of 3-0 nylon were used to secure the skin graft (glued graft). Viable and nonviable areas were traced on a transparent sheet and measured using a Nikon Photomicroscope connected to a KS-300 image analysis system. The skin graft and recipient bed were collected from three dogs at day 7,15, and 30 postoperative. The glued grafs had statistically higher graft viability than sutured grafts. Histological examination showed that the tissue repair process in the glued grafts was more accentuated than sutured grafts. It was possible to conclude that fibrin glue derived from snake venom increased survival of autogenous split-thickness skin graft.
Assuntos
Texto completo: Disponível Coleções: Bases de dados internacionais Base de dados: LILACS Assunto principal: Venenos de Serpentes / Adesivo Tecidual de Fibrina / Transplante de Pele Limite: Animais Idioma: Inglês Revista: J. venom. anim. toxins incl. trop. dis Assunto da revista: Toxicologia Ano de publicação: 2004 Tipo de documento: Artigo País de afiliação: Brasil Instituição/País de afiliação: UNESP/BR / UNOESTE/BR
Texto completo: Disponível Coleções: Bases de dados internacionais Base de dados: LILACS Assunto principal: Venenos de Serpentes / Adesivo Tecidual de Fibrina / Transplante de Pele Limite: Animais Idioma: Inglês Revista: J. venom. anim. toxins incl. trop. dis Assunto da revista: Toxicologia Ano de publicação: 2004 Tipo de documento: Artigo País de afiliação: Brasil Instituição/País de afiliação: UNESP/BR / UNOESTE/BR
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