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Antioxidant activity of extract from Polygonum aviculare L
Hsu, Chin-Yuan.
Afiliação
  • Hsu, Chin-Yuan; Chang Gung University. Department of Life Science. Tao-Yuan. CN
Biol. Res ; 39(2): 281-288, 2006. ilus, tab
Artigo em Inglês | LILACS | ID: lil-432430
Biblioteca responsável: BR1.1
ABSTRACT
Free radicals induce numerous diseases by lipid peroxidation, protein peroxidation, and DNA damage. It has been reported that numerous plant extracts have antioxidant activities to scavenge free radicals. Whether Polygonum aviculare L. (Polygonaceae) has antioxidant activity is unknown. In this study, dried Polygonum aviculare L. was extracted by ethanol, and the extract was lyophilized. The antioxidant activities of extract powder were examined by free radical scavenging assays, superoxide radical scavenging assays, lipid peroxidation assays and hydroxyl radical-induced DNA strand scission assays. The results show that the IC50 value of Polygonum aviculare L. extract is 50 µg/ml in free radical scavenging assays, 0.8 µg/ml in superoxide radical scavenging assays, and 15 µg/ml in lipid peroxidation assays, respectively. Furthermore, Polygonum aviculare L. extract has DNA protective effect in hydroxyl radical-induced DNA strand scission assays. The total phenolics and flavonoid content of extract is 677.4 ± 62.7 µg/g and 112.7 ± 13 µg/g. The results indicate that Polygonum aviculare L. extract clearly has antioxidant effects.
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Texto completo: Disponível Coleções: Bases de dados internacionais Base de dados: LILACS Assunto principal: Dano ao DNA / Peroxidação de Lipídeos / Depuradores de Radicais Livres / Polygonum / Antioxidantes Limite: Animais Idioma: Inglês Revista: Biol. Res Assunto da revista: Biologia Ano de publicação: 2006 Tipo de documento: Artigo / Documento de projeto País de afiliação: China Instituição/País de afiliação: Chang Gung University/CN