Análisis de los factores inmunohistopatológicos (receptores hormonales, estrógenos, progesterona y ERB-2) asociados al pronóstico del cáncer de mama en la población de Barranquilla (2004- 2005) / Analysis of the immunohistopathological factors (hormonal receptors, estrogen, progesterone and ERB-2) associated to the prognosis of breast cancer in the population from Barranquilla (2004- 2005)
Salud UNINORTE
; 23(2): 150-61, dic. 2007. ilus, tab, graf
Artigo
em Espanhol
| LILACS
| ID: lil-480335
Biblioteca responsável:
CO5.1
ABSTRACT
Objectives:
To study the patterns of expression of the estrogen, progestagens and erb-2 receptors in 85 patients attended in two pathology laboratories from Barranquilla, from July 2004 to December 2005. Material andmethods:
This is a descriptive study of cohort. 104 cases were reviewed and 18 were excluded by lack of data. Inmunohistochemistry studies with techniques ofperoxidase - antiperoxidase were made, for which Dako monoclonals antibodies against estrogens, progestagens and ebr-2 were used.Results:
Four neoplasias were classified as carcinoma in situ, one mesenquimal cancer, one lobulillar carcinoma and the others were infiltrating ductal carcinomas grade I, II and III.The immunohistochemistry studies showed positivity for estrogens and progestagen at the intracellular level in 73 cases and negativity to erb-2, 11 were negative for both estrogen and progestagen and one was positive to ebr-2.Conclusions:
1.The infiltrating ductal carcinoma grades II and III were the histological presentation that appears most frequently (80) cases. 2. 88.03 percent of the cases were positive for estrogens and progestagens. 3. The relation between the histological component and the hormonal receptors positivity, suggests a good prognosis.
Texto completo:
Disponível
Coleções:
Bases de dados internacionais
Base de dados:
LILACS
Assunto principal:
Neoplasias da Mama
/
Receptores de Progesterona
/
Estrogênios
Tipo de estudo:
Estudo prognóstico
/
Fatores de risco
Idioma:
Espanhol
Revista:
Salud UNINORTE
Assunto da revista:
Saúde Pública
Ano de publicação:
2007
Tipo de documento:
Artigo
País de afiliação:
Colômbia
Instituição/País de afiliação:
Universidad del Norte/CO