Micronúcleos y otras anormalidades nucleares en el epitelio oral de mujeres expuestas ocupacionalmente a plaguicidas / Micronuclei and other nuclear abnormalities in the oral epithelium of female workers exposed to pesticides
Rev. biol. trop
; 52(3): 611-621, sept. 2004. tab
Artigo
em Espanhol
| LILACS
| ID: lil-501719
Biblioteca responsável:
BR1.1
ABSTRACT
In order to study if banana fields labour exposure to pesticides produces some kind of DNA damage, we determine the presence of micronuclei in epithelial oral cells in working women in Guapiles and Siquirres, Costa Rica, as an effect biomarker. We also analyzed other abnormalities in the nucleus of those cells such as broken-egg, karyolysis or kariorrhexis, to see if there was some kind of genotoxicity or citotoxicity. The women group exposed to pesticides worked in packing bananas plant from different independent farms. The control group of women had never done any farming tasks; they did not live in the banana fields, neither their husband. We got information about the life style, medical and familial history of the participants through an interview. We did not found any significant increment in the frequency of micronuclei form the exposed group compared with the controls. The other nuclei abnormalities showed signs of citotoxicity or genotoxicity in the controls, associated with the intake of coffee and dental x-rays. These results do not rule out at that pesticides used in packing bananas are agents capable of producing damage to the DNA, but it seems that micronuclei from the oral epithelium is not the most adequate marker to measure it.
Texto completo:
Disponível
Coleções:
Bases de dados internacionais
Contexto em Saúde:
ODS3 - Meta 3.9 Reduzir as mortes por produtos químicos y contaminação do ar, água e solo
Problema de saúde:
Exposições Ocupacionais
Base de dados:
LILACS
Assunto principal:
Praguicidas
/
Exposição Ocupacional
/
Aberrações Cromossômicas
/
Musa
/
Agricultura
/
Mucosa Bucal
Tipo de estudo:
Estudo observacional
/
Fatores de risco
Limite:
Adolescente
/
Adulto
/
Feminino
/
Humanos
País/Região como assunto:
América Central
/
Costa Rica
Idioma:
Espanhol
Revista:
Rev. biol. trop
Assunto da revista:
Biologia
/
Medicina Tropical
Ano de publicação:
2004
Tipo de documento:
Artigo
País de afiliação:
Costa Rica
Instituição/País de afiliação:
Universidad de Costa Rica/CR