Risk of catecholamine crisis in patients undergoing resection of unsuspected pheochromocytoma
Int. braz. j. urol
; 37(1): 35-41, Jan.-Feb. 2011. ilus, tab
Artigo
em Inglês
| LILACS
| ID: lil-581535
Biblioteca responsável:
BR1.1
ABSTRACT
PURPOSE:
To report the risk of catecholamine crisis in patients undergoing resection of unsuspected pheochromocytoma. MATERIALS ANDMETHODS:
Over a four-year period, we retrospectively identified four patients who underwent resection of adrenal pheochromocytoma in whom the diagnosis was unsuspected based on preoperative clinical, biochemical, and imaging evaluation.RESULTS:
None of the patients exhibited preoperative clinical features of catecholamine excess. Preoperative biochemical screening in two patients was normal. CT scan performed in all patients demonstrated a nonspecific enhancing adrenal mass. During surgical resection of the adrenal mass, hemodynamic instability was observed in two of four patients, and one of these two patients also suffered a myocardial infarct.CONCLUSION:
Both surgeons and radiologists should maintain a high index of suspicion for pheochromocytoma, as the tumor can be asymptomatic, biochemically negative, and have nonspecific imaging features. Resection of such unsuspected pheochromocytomas carries a substantial risk of intraoperative hemodynamic instability.
Texto completo:
Disponível
Coleções:
Bases de dados internacionais
Base de dados:
LILACS
Assunto principal:
Feocromocitoma
/
Catecolaminas
/
Neoplasias das Glândulas Suprarrenais
/
Complicações Intraoperatórias
Tipo de estudo:
Estudo de etiologia
/
Estudo observacional
/
Estudo prognóstico
Limite:
Adulto
/
Idoso
/
Feminino
/
Humanos
/
Masculino
Idioma:
Inglês
Revista:
Int. braz. j. urol
Assunto da revista:
Urologia
Ano de publicação:
2011
Tipo de documento:
Artigo
País de afiliação:
Estados Unidos
Instituição/País de afiliação:
University of California San Francisco/US