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Severity classification for idiopathic pulmonary fibrosis by using fuzzy logic
Lopes, Agnaldo José; Capone, Domenico; Mogami, Roberto; Lanzillotti, Regina Serrão; Melo, Pedro Lopes de; Jansen, José Manoel.
Afiliação
  • Lopes, Agnaldo José; State University of Rio de Janeiro. Pulmonary Function Laboratory. Rio de Janeiro. BR
  • Capone, Domenico; State University of Rio de Janeiro. Pulmonary Function Laboratory. Rio de Janeiro. BR
  • Mogami, Roberto; State University of Rio de Janeiro. Division of Radiology. Rio de Janeiro. BR
  • Lanzillotti, Regina Serrão; State University of Rio de Janeiro. Institute of Mathematics and Statistics. Rio de Janeiro. BR
  • Melo, Pedro Lopes de; State University of Rio de Janeiro. Biomedical Instrumentation Laboratory. Rio de Janeiro. BR
  • Jansen, José Manoel; State University of Rio de Janeiro. Pulmonary Function Laboratory. Rio de Janeiro. BR
Clinics ; 66(6): 1015-1019, 2011. tab
Artigo em Inglês | LILACS | ID: lil-594371
Biblioteca responsável: BR1.1
ABSTRACT

OBJECTIVE:

To set out a severity classification for idiopathic pulmonary fibrosis (IPF) based on the interaction of pulmonary function parameters with high resolution computed tomography (CT) findings.

INTRODUCTION:

Despite the contribution of functional and radiological methods in the study of IPF, there are few classification proposals for the disease based on these examinations.

METHODS:

A cross-sectional study was carried out, in which 41 non-smoking patients with IPF were evaluated. The following high resolution CT findings were quantified using a semi-quantitative scoring system reticular abnormality, honeycombing and ground-glass opacity. The functional variables were measured by spirometry, forced oscillation technique, helium dilution method, as well as the single-breath method of diffusing capacity of carbon monoxide. With the interaction between functional indexes and high resolution CT scores through fuzzy logic, a classification for IPF has been built.

RESULTS:

Out of 41 patients studied, 26 were male and 15 female, with a mean age of 70.8 years. Volume measurements were the variables which showed the best interaction with the disease extension on high resolution CT, while the forced vital capacity showed the lowest estimative errors in comparison to total lung capacity. A classification for IPF was suggested based on the 95 percent confidence interval of the forced vital capacity percent mild group (>92.7); moderately mild (76.9-92.6); moderate (64.3-76.8 percent); moderately severe (47.1-64.2); severe (24.3-47.0); and very severe (<24.3).

CONCLUSION:

Through fuzzy logic, an IPF classification was built based on forced vital capacity measurement with a simple practical application.
Assuntos


Texto completo: Disponível Coleções: Bases de dados internacionais Base de dados: LILACS Assunto principal: Índice de Gravidade de Doença / Lógica Fuzzy / Fibrose Pulmonar Idiopática Tipo de estudo: Estudo observacional / Estudo de prevalência / Estudo prognóstico / Fatores de risco Limite: Idoso / Feminino / Humanos / Masculino Idioma: Inglês Revista: Clinics Assunto da revista: Medicina Ano de publicação: 2011 Tipo de documento: Artigo País de afiliação: Brasil Instituição/País de afiliação: State University of Rio de Janeiro/BR

Texto completo: Disponível Coleções: Bases de dados internacionais Base de dados: LILACS Assunto principal: Índice de Gravidade de Doença / Lógica Fuzzy / Fibrose Pulmonar Idiopática Tipo de estudo: Estudo observacional / Estudo de prevalência / Estudo prognóstico / Fatores de risco Limite: Idoso / Feminino / Humanos / Masculino Idioma: Inglês Revista: Clinics Assunto da revista: Medicina Ano de publicação: 2011 Tipo de documento: Artigo País de afiliação: Brasil Instituição/País de afiliação: State University of Rio de Janeiro/BR
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