Interventions in the neonatal environment in rats and their relationship to behavior in adulthood and maternal behavior
Psychol. neurosci. (Impr.)
; 3(1): 73-78, Jan.-June 2010. ilus
Artigo
em Inglês
| LILACS
| ID: lil-604504
Biblioteca responsável:
BR85.1
ABSTRACT
The objective of this study was to assess the role of environmental/nest components and maternal behavior after several neonatal interventions on subsequent behavioral responses. Male Wistar rats were subjected to different neonatal interventions and were later evaluated for innate fear-like behavior in adulthood. The experimental groups included nonhandled (i.e., animals were not touched), handled (i.e., animals were separated from their mother, removed from the nest, and handled for 10 min/day), brief maternal separation (i.e., the mother was removed from the homecage for 10 min/day, and the pups remained in their cages without being touched), and tactile stimulation (i.e., the mother was removed from the homecage, and pups were stimulated with a brush for 10 min/day within the nest). The mother's behavior was recorded during the neonatal period, and the male pups were later tested in the open field as adults. The results revealed that only mothers whose pups were handled had an increase in the duration of licking behavior compared with the other groups. In the open field test, we observed decreased behavioral innate fear-like responses in male adults in the handled and brief separation groups compared with the others groups. Our results confirm that interventions during the neonatal period cause stable behavioral changes (decreased innate fear) in adulthood and that absent or excessive tactile stimulation appears to be an important factor. Both repeated disruption of the mother-infant relationship and withdrawal from the environment/nest are factors that exert profound effects on the development of the animals.
Texto completo:
Disponível
Coleções:
Bases de dados internacionais
Contexto em Saúde:
ODS3 - Meta 3.1 Reduzir a Mortalidade Materna
Problema de saúde:
Cuidado Materno
Base de dados:
LILACS
Assunto principal:
Comportamento Animal
/
Ambiente Controlado
/
Comportamento Materno
Tipo de estudo:
Estudo prognóstico
Idioma:
Inglês
Revista:
Psychol. neurosci. (Impr.)
Assunto da revista:
Neurologia
/
Psicologia
Ano de publicação:
2010
Tipo de documento:
Artigo
País de afiliação:
Brasil
Instituição/País de afiliação:
Pontifícia Universidade Católica do Rio Grande do Sul/BR
/
Universidade Federal de Ciências da Saúde de Porto Alegre/BR
/
Universidade Federal do Rio Grande do Sul/BR