Cross self-administration of delta 9 tetrahydrocannabinol and D-amphetamine in rats
Braz. j. med. biol. res
; 14(6): 395-400, Dec. 1981. ilus, tab
Artigo
em Inglês
| LILACS
| ID: lil-61886
Biblioteca responsável:
BR26.1
ABSTRACT
1. Schedule-induced intravenous self-injection of delta9 - tetrahydrocannabinol (delta9 -THC) and d-amphetamine was investigated in the same animals. 2. /rats self-injected significantly more amphetamine than delta9 -THC. However, the results suggested that delta9 -THC did not play a predisposing role to the increased amphetamine intake. When delta 9 -THC was reinstated after amphetamine response rates were drastically reduced. 3. It is conclued that the reinforcing effects of delta- -THC may be unrelated to its stimulant effects. The small number of responses for delta9 -THC is in agreement with reports of the poor reinforcing capability of cannabis compounds in rats
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Base de dados:
LILACS
Assunto principal:
Dronabinol
/
Peso Corporal
/
Autoadministração
/
Dextroanfetamina
Limite:
Animais
Idioma:
Inglês
Revista:
Braz. j. med. biol. res
Assunto da revista:
Biologia
/
Medicina
Ano de publicação:
1981
Tipo de documento:
Artigo