Behavioral effects of neurotensin applied to periventricular structures of rats
Braz. j. med. biol. res
; 22(6): 711-5, June 1989. ilus
Artigo
em Inglês
| LILACS
| ID: lil-75176
Biblioteca responsável:
BR26.1
ABSTRACT
Neurotensin (NT), n active neuropeptide, and bicuculline, a GABA-A receptor antagonist, were microinjected into the rat hypothalaamus (MH) or the dorsal periaqueductal gray matter (DPAG). Bicuculline (80 pmol) produced behavioral activation which included jumping and NT (1-20 nmol) caused a dose-dependent behavioral activation accompanied by catalepsy rather than jumping. These results suggest that the behavioral activation produced by NT may be due to an interaction of the neuropeptide with specific receptors while its cataleptic effect may be attributed to the blockade of dopamine receptors
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Bases de dados internacionais
Base de dados:
LILACS
Assunto principal:
Comportamento de Esquiva
/
Bicuculina
/
Neurotensina
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Substância Cinzenta Periaquedutal
/
Hipotálamo Médio
Limite:
Animais
Idioma:
Inglês
Revista:
Braz. j. med. biol. res
Assunto da revista:
Biologia
/
Medicina
Ano de publicação:
1989
Tipo de documento:
Artigo
/
Congresso e conferência
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Documento de projeto