Immediate postoperative evaluation of enteric anastomosis after the use of meloxicam in rats
Acta cir. bras
; 31(5): 320-326, May 2016. tab, graf
Artigo
em Inglês
| LILACS
| ID: lil-783801
Biblioteca responsável:
BR1.1
ABSTRACT
ABSTRACT PURPOSE:
To compare ileal anastomoses in the immediate postoperative healing period after meloxicam use.METHODS:
Forty two male Wistar rats were randomly divided into two groups of 21, COX and control group. To COX meloxicam in combination with morphine was given in 3 days period. Control group received only morphine during the same period. Each group was divided into three sub-groups of 7, which were euthanized at 5, 10, and 21 days postoperatively. Comparison was based in histological evaluation of collagen type I and III using sirius red, immunohistochemical through vascular endothelial growth factor and matrix metalloproteinase-9.RESULTS:
Healing process in scheduled periods did not show significant differences (p>0.05) between the COX and control groups during any of the periods.CONCLUSION:
The use of meloxicam in the postoperative period following ileal anastomosis did not affect healing.
Texto completo:
Disponível
Coleções:
Bases de dados internacionais
Base de dados:
LILACS
Assunto principal:
Tiazinas
/
Tiazóis
/
Cicatrização
/
Anti-Inflamatórios não Esteroides
/
Inibidores de Ciclo-Oxigenase
/
Íleo
Tipo de estudo:
Estudo prognóstico
Limite:
Animais
Idioma:
Inglês
Revista:
Acta cir. bras
Assunto da revista:
CIRURGIA GERAL
/
Procedimentos Cir£rgicos Operat¢rios
Ano de publicação:
2016
Tipo de documento:
Artigo
País de afiliação:
Brasil
Instituição/País de afiliação:
Pontificia Universidade Católica do Paraná/BR