Your browser doesn't support javascript.
loading
Starvation and refeeding in rats: effect on some parameters of energy metabolism and electrolytes and changes of hepatic tissue
Namazi, Fatemeh; Omidi, Arash; Abbasi, Sajjad; Afsar, Mina; Honarmand, Masumeh; Nazifi, Saeed.
Afiliação
  • Namazi, Fatemeh; Shiraz University. School of Veterinary Medicine. Department of Pathobiology. Shiraz. IR
  • Omidi, Arash; Shiraz University. School of Veterinary Medicine. Department of Animal Health Management. Shiraz. IR
  • Abbasi, Sajjad; Shiraz University. School of Veterinary Medicine. Shiraz. IR
  • Afsar, Mina; Shiraz University. School of Veterinary Medicine. Department of Clinical Studies. Shiraz. IR
  • Honarmand, Masumeh; Shiraz University. School of Veterinary Medicine. Department of Clinical Studies. Shiraz. IR
  • Nazifi, Saeed; Shiraz University. School of Veterinary Medicine. Department of Clinical Studies. Shiraz. IR
Pesqui. vet. bras ; 36(supl.1): 101-105, June 2016. tab, graf, ilus
Artigo em Inglês | LILACS, VETINDEX | ID: lil-798008
Biblioteca responsável: BR1.1
ABSTRACT
Regarding the importance of starvation and refeeding and the occurrence of refeeding syndrome in various conditions, the present study was conducted to investigate the effects of refeeding on some parameters of energy metabolism and electrolytes and changes of hepatic tissue in male Wistar rats. Fifty-seven rats were divided into six groups, having 6 to 11 rats. Food was provided ad-libitum until three months and then the first group was considered without starvation (day 0). Other rats were fasted for two weeks. Group 2 was applied to a group immediately after starvation (day 14). Groups 3 to 6 were refed in days 16 till 22, respectively. At the end of each period, blood and tissue samples were taken and histopathological and serum analysis, including serum electrolytes (calcium, phosphorus, sodium, potassium), the energy parameters (glucose, insulin, cortisol) and the liver enzymes (ALT, AST, ALP) were determined. Insulin decreased by starvation and then showed an increasing trend compared to starvation period, which the highest amount of this parameter was observed eight days post-refeeding. Serum glucose level showed the opposite pattern of insulin. Histopathological examination of the tissue sections revealed clear vacuoles after starvation and refeeding, in which the severity of lesions gradually decreased during refeeding. The cortisol level decreased by starvation and then increased during refeeding. Also, potassium and phosphorus concentrations declined by refeeding and the serum sodium and potassium levels were changed in the relatively opposite manner. The calcium level decreased by starvation and then increased during refeeding. These results could help recognize and remedy the refeeding syndrome.(AU)
Assuntos

Texto completo: Disponível Coleções: Bases de dados internacionais Base de dados: LILACS / VETINDEX Assunto principal: Jejum / Ratos Wistar / Eletrólitos / Fígado Limite: Animais Idioma: Inglês Revista: Pesqui. vet. bras Assunto da revista: Medicina Veterinária Ano de publicação: 2016 Tipo de documento: Artigo / Documento de projeto País de afiliação: Irã Instituição/País de afiliação: Shiraz University/IR

Similares

MEDLINE

...
LILACS

LIS


Texto completo: Disponível Coleções: Bases de dados internacionais Base de dados: LILACS / VETINDEX Assunto principal: Jejum / Ratos Wistar / Eletrólitos / Fígado Limite: Animais Idioma: Inglês Revista: Pesqui. vet. bras Assunto da revista: Medicina Veterinária Ano de publicação: 2016 Tipo de documento: Artigo / Documento de projeto País de afiliação: Irã Instituição/País de afiliação: Shiraz University/IR
...