[Effectiveness of isoniazid inhalation in patients with endobronchial tuberculosis].
Nihon Kokyuki Gakkai Zasshi
; 37(1): 31-5, 1999 Jan.
Article
em Ja
| MEDLINE
| ID: mdl-10087873
ABSTRACT
The clinical effectiveness of isoniazid (INH) inhalation was studied retrospectively in 34 patients with endobronchial tuberculosis. Diagnoses of endobronchial tuberculosis and assessments of bronchial stenosis were based on bronchoscopic examinations. We divided the patients into 2 groups 13 who received systemic chemotherapy for lung tuberculosis only, and 21 who received systemic chemotherapy combined with INH inhalation (200 mg/day). No significant differences distinguished the groups with respect to duration of positive sputum culture or ESR normalization. However, a significant alleviation of bronchial stenosis and earlier reduction of respiratory symptoms were observed in the patients who received systemic chemotherapy with INH inhalation. We concluded that INH inhalation in addition to standard therapy for lung tuberculosis is effective in patients with endobronchial tuberculosis.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Tuberculose Pulmonar
/
Broncopatias
/
Isoniazida
/
Antituberculosos
Tipo de estudo:
Observational_studies
/
Risk_factors_studies
Limite:
Adult
/
Aged
/
Aged80
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
Ja
Revista:
Nihon Kokyuki Gakkai Zasshi
Ano de publicação:
1999
Tipo de documento:
Article
País de afiliação:
Japão