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Prevalence of anemia and renal insufficiency in non-hospitalized patients with heart failure.
Arq Bras Cardiol ; 93(3): 268-74, 2009 Sep.
Artigo em Inglês, Português, Espanhol | MEDLINE | ID: mdl-19851655


Heart Failure (HF) is a common disease with a high rate of mortality. Anemia and renal failure (RF) are often found in patients with HF associated with higher severity of the heart disease and a worse prognosis.


To evaluate the prevalence of anemia and RF, as well as the association between these two conditions, in non-hospitalized patients with HF.


Patients treated at the HF Outpatient Clinic of a university hospital were followed from July 2003 to November 2006. Anemia was defined as hemoglobin levels < 13 mg/dl for men and 12 mg/dl for women. Renal function was assessed by the glomerular filtration rate (GFR), calculated by the simplified formula of the MDRD (Modification of Diet in Renal Disease) study.


Of the 345 patients included in this study, 26.4% (n = 91) had anemia and 29.6% had moderate to severe renal failure (GFR < 60 ml/min). The association between anemia and a higher prevalence of renal failure was statistically significant (41.8% vs. 25.2%; p = 0.005). The patients at functional class III and IV presented a higher incidence of anemia (39.0% vs. 19.4%; p <0.001) and renal failure (38.2% vs. 24.8%; p = 0.007). No association was observed between anemia or renal failure and history of hypertension, diabetes, systolic function or etiology of HF.


The prevalence of anemia and renal failure was high in this population and was associated with the severity of the HF (functional classes III and IV).





Texto completo: Disponível Coleções: Bases de dados internacionais Base de dados: MEDLINE Assunto principal: Pacientes Ambulatoriais / Insuficiência Renal / Insuficiência Cardíaca / Anemia Aspecto clínico: Prognóstico Limite: Feminino / Humanos / Masculino / Meia-Idade País/Região como assunto: América do Sul / Brasil Idioma: Inglês / Espanhol / Português Revista: Arq Bras Cardiol Ano de publicação: 2009 Tipo de documento: Artigo País de afiliação: Brasil