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Prevalence of anemia and renal insufficiency in non-hospitalized patients with heart failure.
Arq Bras Cardiol ; 93(3): 268-74, 2009 Sep.
Artigo em Inglês, Português, Espanhol | MEDLINE | ID: mdl-19851655
ABSTRACT

BACKGROUND:

Heart Failure (HF) is a common disease with a high rate of mortality. Anemia and renal failure (RF) are often found in patients with HF associated with higher severity of the heart disease and a worse prognosis.

OBJECTIVE:

To evaluate the prevalence of anemia and RF, as well as the association between these two conditions, in non-hospitalized patients with HF.

METHODS:

Patients treated at the HF Outpatient Clinic of a university hospital were followed from July 2003 to November 2006. Anemia was defined as hemoglobin levels < 13 mg/dl for men and 12 mg/dl for women. Renal function was assessed by the glomerular filtration rate (GFR), calculated by the simplified formula of the MDRD (Modification of Diet in Renal Disease) study.

RESULTS:

Of the 345 patients included in this study, 26.4% (n = 91) had anemia and 29.6% had moderate to severe renal failure (GFR < 60 ml/min). The association between anemia and a higher prevalence of renal failure was statistically significant (41.8% vs. 25.2%; p = 0.005). The patients at functional class III and IV presented a higher incidence of anemia (39.0% vs. 19.4%; p <0.001) and renal failure (38.2% vs. 24.8%; p = 0.007). No association was observed between anemia or renal failure and history of hypertension, diabetes, systolic function or etiology of HF.

CONCLUSION:

The prevalence of anemia and renal failure was high in this population and was associated with the severity of the HF (functional classes III and IV).
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Texto completo: Disponível Coleções: Bases de dados internacionais Base de dados: MEDLINE Assunto principal: Pacientes Ambulatoriais / Insuficiência Renal / Insuficiência Cardíaca / Anemia Aspecto clínico: Prognóstico Limite: Feminino / Humanos / Masculino / Meia-Idade País/Região como assunto: América do Sul / Brasil Idioma: Inglês / Espanhol / Português Revista: Arq Bras Cardiol Ano de publicação: 2009 Tipo de documento: Artigo País de afiliação: Brasil