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[Epidemiological study of thalasaemia among children in Xishuangbanna, Dehong and Nujiang of Yunnan province].
Zhonghua Yi Xue Yi Chuan Xue Za Zhi ; 28(5): 579-82, 2011 Oct.
Artigo em Chinês | MEDLINE | ID: mdl-21983740
ABSTRACT

OBJECTIVE:

To investigate the carrier rate of thalasaemia among the children of 10 minority ethnic groups in 3 border states (Xishuangbanna, Dehong and Nujiang) of Yunnan Province.

METHODS:

A total of 6562 samples of children under 10 years old were analyzed by blood cell automatic analysis and hemoglobin electrophoresis.

RESULTS:

The overall carrier frequency of thalasaemia was highest (46.2%) in Dehong, and lowest (30.6%) in Nujiang. The carrier frequency of beta-thalasaemia was the highest (40.6%) in Achang, and lowest (2.5%) in Dulong. The carrier frequency of alpha-thalasaemia was the highest (22.1%) in Dai from Xishuangbanna, followed by Dulong (19.1%).

CONCLUSION:

Thalasaemia carrier rates were high among the children of 10 minority ethnic groups in Yunnan. There were regional differences in their incidences. The results provide a valuable basis for thalasaemia prevention in Yunnan minorities in the three border states.
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Texto completo: Disponível Coleções: Bases de dados internacionais Base de dados: MEDLINE Assunto principal: Talassemia / Grupos Minoritários Tipo de estudo: Prevalence_studies Limite: Criança / Criança, pré-escolar / Humanos / Lactente / Recém-Nascido País/Região como assunto: Ásia Idioma: Chinês Revista: Zhonghua Yi Xue Yi Chuan Xue Za Zhi Assunto da revista: Genética Médica Ano de publicação: 2011 Tipo de documento: Artigo