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Estimation of the common risk difference in stratified paired binary data with homogeneous stratum effect.
J Biopharm Stat ; 23(4): 848-55, 2013.
Artigo em Inglês | MEDLINE | ID: mdl-23786205
ABSTRACT
McNemar's test is commonly used to test for the risk difference between two binary variables on matched pairs. For stratified paired binary data, recently a test for the homogeneous stratum effect (HSE) has been developed. If HSE is rejected, then McNemar's test should be applied by stratum; otherwise, in this article we propose a concept of common risk difference (CRD) across the strata and derive point estimators and confidence intervals for CRD. We use a cancer study for illustration and conduct simulations to recommend point estimators and associated confidence intervals with good statistical properties.
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Texto completo: Disponível Coleções: Bases de dados internacionais Base de dados: MEDLINE Assunto principal: Intervalos de Confiança / Ensaios Clínicos como Assunto / Modelos Estatísticos / Análise por Pareamento Aspecto clínico: Etiologia / Terapia Limite: Feminino / Humanos Idioma: Inglês Revista: J Biopharm Stat Assunto da revista: Farmacologia Ano de publicação: 2013 Tipo de documento: Artigo País de afiliação: Estados Unidos