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Molecular functions of the iron-regulated metastasis suppressor, NDRG1, and its potential as a molecular target for cancer therapy.
Fang, Bernard A; Kovacevic, Zaklina; Park, Kyung Chan; Kalinowski, Danuta S; Jansson, Patric J; Lane, Darius J R; Sahni, Sumit; Richardson, Des R.
Afiliação
  • Fang BA; Molecular Pharmacology and Pathology Program, Discipline of Pathology and Bosch Institute, Blackburn Building (D06), The University of Sydney, Sydney, NSW 2006, Australia.
  • Kovacevic Z; Molecular Pharmacology and Pathology Program, Discipline of Pathology and Bosch Institute, Blackburn Building (D06), The University of Sydney, Sydney, NSW 2006, Australia.
  • Park KC; Molecular Pharmacology and Pathology Program, Discipline of Pathology and Bosch Institute, Blackburn Building (D06), The University of Sydney, Sydney, NSW 2006, Australia.
  • Kalinowski DS; Molecular Pharmacology and Pathology Program, Discipline of Pathology and Bosch Institute, Blackburn Building (D06), The University of Sydney, Sydney, NSW 2006, Australia.
  • Jansson PJ; Molecular Pharmacology and Pathology Program, Discipline of Pathology and Bosch Institute, Blackburn Building (D06), The University of Sydney, Sydney, NSW 2006, Australia.
  • Lane DJ; Molecular Pharmacology and Pathology Program, Discipline of Pathology and Bosch Institute, Blackburn Building (D06), The University of Sydney, Sydney, NSW 2006, Australia.
  • Sahni S; Molecular Pharmacology and Pathology Program, Discipline of Pathology and Bosch Institute, Blackburn Building (D06), The University of Sydney, Sydney, NSW 2006, Australia.
  • Richardson DR; Molecular Pharmacology and Pathology Program, Discipline of Pathology and Bosch Institute, Blackburn Building (D06), The University of Sydney, Sydney, NSW 2006, Australia. Electronic address: d.richardson@med.usyd.edu.au.
Biochim Biophys Acta ; 1845(1): 1-19, 2014 Jan.
Article em En | MEDLINE | ID: mdl-24269900
Assuntos
Palavras-chave
2-hydroxy-1-naphthaldehyde isonicotinoyl hydrazone; 70-kDa heat shock cognate protein; Akt; CMT4D; CPT-11; Charcot­Marie­Tooth disease, type 4D; DFO; Dp44mT; DpC; DpT; ECM; EGR1; ERG-1; ETS; HDL-C; HIF-1α; HMSNL; HTE; HUVEC; Hsc70; IL; LDL; LPC; MMP; Metastasis suppressor; N-myc down-regulated gene 1; N-myc down-stream regulated gene 1; NDRG1; NF-κB; NIH; PAR-1; PKA; PTEN; PrEC; ROCK1; ROS; Rho-associated, coiled-coil containing protein kinase 1 (ROCK1); SGK; T-cell factor/lymphoid enhancer-binding factor; TAT; TAT2; TCF/LEF; Thiosemicarbazone; Thtpa; VEGF; deferoxamine (or desferrioxamine B); di-2-pyridylketone 4,4-dimethyl-3-thiosemicarbazone; di-2-pyridylketone 4-cyclohexyl-4-methyl-3-thiosemicarbazone; di-2-pyridylketone thiosemicarbazone; early growth factor-1; extracellular matrix; hereditary motor and sensory neuropathy-Lom; high-density lipoprotein cholesterol; human tracheal epithelial cell; human umbilical vein endothelial cell; hypoxia inducible factor-1α; interleukin; irinotecan; low-density lipoprotein; lysophosphatidylcholine; matrix metalloproteinase; nuclear factor-κB; pMLC2; pVHL; phosphatase and tensin homologue deleted on chromosome 10; phosphorylated myosin light chain 2; prostate epithelial cell; protease activated receptor; protein kinase A; protein kinase B; protein kinase C; reactive oxygen species; serum- and glucocorticoid-induced kinase; thiamine triphosphatase; tumour-associated trypsinogen; tumour-associated trypsinogen-2; v-ets avian erythroblastosis virus E26 oncogene homologue; v-ets avian erythroblastosis virus E26 oncogene homologue 2; vascular endothelial growth factor; von Hippel­Lindau protein
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas de Ciclo Celular / Proteínas Supressoras de Tumor / Peptídeos e Proteínas de Sinalização Intracelular / Neoplasias Limite: Animals / Humans Idioma: En Revista: Biochim Biophys Acta Ano de publicação: 2014 Tipo de documento: Article País de afiliação: Austrália País de publicação: Holanda
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas de Ciclo Celular / Proteínas Supressoras de Tumor / Peptídeos e Proteínas de Sinalização Intracelular / Neoplasias Limite: Animals / Humans Idioma: En Revista: Biochim Biophys Acta Ano de publicação: 2014 Tipo de documento: Article País de afiliação: Austrália País de publicação: Holanda