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The HSP90 inhibitor 17-N-allylamino-17-demethoxy geldanamycin (17-AAG) synergizes with cisplatin and induces apoptosis in cisplatin-resistant esophageal squamous cell carcinoma cell lines via the Akt/XIAP pathway.
Ui, Takashi; Morishima, Kazue; Saito, Shin; Sakuma, Yuji; Fujii, Hirofumi; Hosoya, Yoshinori; Ishikawa, Shumpei; Aburatani, Hiroyuki; Fukayama, Masashi; Niki, Toshiro; Yasuda, Yoshikazu.
Afiliação
  • Ui T; Department of Surgery, Jichi Medical University, Shimotsuke, Tochigi 329-0498, Japan.
  • Morishima K; Department of Surgery, Jichi Medical University, Shimotsuke, Tochigi 329-0498, Japan.
  • Saito S; Department of Surgery, Jichi Medical University, Shimotsuke, Tochigi 329-0498, Japan.
  • Sakuma Y; Department of Pathology, Jichi Medical University, Shimotsuke, Tochigi 329-0498, Japan.
  • Fujii H; Department of Clinical Oncology, Jichi Medical University, Shimotsuke, Tochigi 329-0498, Japan.
  • Hosoya Y; Department of Surgery, Jichi Medical University, Shimotsuke, Tochigi 329-0498, Japan.
  • Ishikawa S; Division of Genomic Pathology, Medical Research Institute, Tokyo Medical and Dental University, Bunkyo-ku, Tokyo 113-8510, Japan.
  • Aburatani H; Division of Genome Science, Research Center for Advanced Science and Technology, the University of Tokyo, Meguro-ku, Tokyo 153-8904, Japan.
  • Fukayama M; Department of Pathology, Graduate School of Medicine, the University of Tokyo, Bunkyo-ku, Tokyo 113-0033, Japan.
  • Niki T; Department of Pathology, Jichi Medical University, Shimotsuke, Tochigi 329-0498, Japan.
  • Yasuda Y; Department of Surgery, Jichi Medical University, Shimotsuke, Tochigi 329-0498, Japan.
Oncol Rep ; 31(2): 619-24, 2014 Feb.
Article em En | MEDLINE | ID: mdl-24317439
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Esofágicas / Carcinoma de Células Escamosas / Benzoquinonas / Cisplatino / Apoptose / Lactamas Macrocíclicas Limite: Humans Idioma: En Revista: Oncol Rep Assunto da revista: NEOPLASIAS Ano de publicação: 2014 Tipo de documento: Article País de afiliação: Japão País de publicação: Grécia
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Esofágicas / Carcinoma de Células Escamosas / Benzoquinonas / Cisplatino / Apoptose / Lactamas Macrocíclicas Limite: Humans Idioma: En Revista: Oncol Rep Assunto da revista: NEOPLASIAS Ano de publicação: 2014 Tipo de documento: Article País de afiliação: Japão País de publicação: Grécia