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El déficit de vitamina D se asocia a factores de riesgo en personas sin antecedentes cardiovasculares. / [Vitamin D deficiency is associated with cardiovascular risk factors in a healthy population].
Artigo em Espanhol | MEDLINE | ID: mdl-24650652
RESUMEN
Vitamin D (VitD) deficiency is associated with increased morbidity and mortality. We evaluated the association of VitD deficiency (<50 mmol/l) and cardiovascular risk factors in a healthy population, from July-November 2012, in a private center at Buenos Aires province. 333 people were included, aged 41.6±12.4 years (58.6% men), 49.2% practiced no physical activity, 56.8% were overweight (70.3% man vs 37.7% women, p<0.001), 12.5% with systolic blood pressure (SBP) >140 mmHg and 6% diastolic blood pressure (DBP) >90 mmHg. VitD deficiency was observed in 29.1% (31.3% man vs 26.1% women, p=0.3), more frequent with obesity (OR 1.85, IC951.05-3.25, p=0.02), HDL-cholesterol (HDL-C)<50 mg/dl (OR 1.71, IC951.06-2.76, p=0.02) and triglycerides>150 mg/dl (OR 1.77, IC951.02-3.06, p=0.03). A trend towards VitD deficiency and SBP>140 mmHg (OR 1.88, IC950.93-3.77, p=0.07) or DBP>90 mmHg (OR 1.39, IC950.5-3.65, p=0.5) was observed. Lineal correlation between VitD and HDL-C (p<0.001) or triglycerides (p<0.001) was observed. Multiple logistic regression showed that VitD deficiency association with low HDL-C was independent of age, female sex, obesity and physical activity. Association of VitD deficiency with hypetriglyceridemia was independent of age, female sex and obesity. This study shows an association between VitD deficiency and cardiovascular risk factors like obesity, low HDL <50 mg/dl and hypertriglyceridemia. A trend toward higher SBP was also observed. Experimental studies are granted in order to establish a cause-effect relationship.
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Coleções: Bases de dados internacionais Base de dados: MEDLINE Assunto principal: Deficiência de Vitamina D / Doenças Cardiovasculares Aspecto clínico: Etiologia Limite: Adulto / Feminino / Humanos / Masculino / Meia-Idade Idioma: Espanhol Revista: Rev Fac Cien Med Univ Nac Cordoba Ano de publicação: 2013 Tipo de documento: Artigo