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Observation of small cluster formation in concentrated monoclonal antibody solutions and its implications to solution viscosity.
Yearley, Eric J; Godfrin, Paul D; Perevozchikova, Tatiana; Zhang, Hailiang; Falus, Peter; Porcar, Lionel; Nagao, Michihiro; Curtis, Joseph E; Gawande, Pradad; Taing, Rosalynn; Zarraga, Isidro E; Wagner, Norman J; Liu, Yun.
Afiliação
  • Yearley EJ; Center for Neutron Research, National Institute of Standards and Technology, Gaithersburg, Maryland; Department of Chemical and Biomolecular Engineering, Center for Neutron Science, University of Delaware, Newark, Delaware.
  • Godfrin PD; Center for Neutron Research, National Institute of Standards and Technology, Gaithersburg, Maryland; Department of Chemical and Biomolecular Engineering, Center for Neutron Science, University of Delaware, Newark, Delaware.
  • Perevozchikova T; Center for Neutron Research, National Institute of Standards and Technology, Gaithersburg, Maryland; Department of Chemical and Biomolecular Engineering, Center for Neutron Science, University of Delaware, Newark, Delaware.
  • Zhang H; Center for Neutron Research, National Institute of Standards and Technology, Gaithersburg, Maryland; Institute for Research and Applied Physics, University of Maryland, College Park, Maryland.
  • Falus P; Institut Laue-Langevin, Grenoble, France.
  • Porcar L; Institut Laue-Langevin, Grenoble, France.
  • Nagao M; Center for Neutron Research, National Institute of Standards and Technology, Gaithersburg, Maryland; Center for Exploration of Energy and Matter, Indiana University, Bloomington, Indiana.
  • Curtis JE; Center for Neutron Research, National Institute of Standards and Technology, Gaithersburg, Maryland.
  • Gawande P; Theranos Inc., Palo Alto, California.
  • Taing R; Late Stage Pharmaceutical Development, Genentech Inc., South San Francisco, California.
  • Zarraga IE; Late Stage Pharmaceutical Development, Genentech Inc., South San Francisco, California. Electronic address: zarraga.isidro@gene.com.
  • Wagner NJ; Department of Chemical and Biomolecular Engineering, Center for Neutron Science, University of Delaware, Newark, Delaware.
  • Liu Y; Center for Neutron Research, National Institute of Standards and Technology, Gaithersburg, Maryland; Department of Chemical and Biomolecular Engineering, Center for Neutron Science, University of Delaware, Newark, Delaware. Electronic address: yunliu@udel.edu.
Biophys J ; 106(8): 1763-70, 2014 Apr 15.
Article em En | MEDLINE | ID: mdl-24739175

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Agregados Proteicos / Anticorpos Monoclonais Limite: Humans Idioma: En Revista: Biophys J Ano de publicação: 2014 Tipo de documento: Article País de publicação: Estados Unidos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Agregados Proteicos / Anticorpos Monoclonais Limite: Humans Idioma: En Revista: Biophys J Ano de publicação: 2014 Tipo de documento: Article País de publicação: Estados Unidos