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Identification of T. gondii myosin light chain-1 as a direct target of TachypleginA-2, a small-molecule inhibitor of parasite motility and invasion.
Leung, Jacqueline M; Tran, Fanny; Pathak, Ravindra B; Poupart, Séverine; Heaslip, Aoife T; Ballif, Bryan A; Westwood, Nicholas J; Ward, Gary E.
Afiliação
  • Leung JM; Department of Microbiology and Molecular Genetics, University of Vermont, Burlington, Vermont, United States of America; Program in Cellular and Molecular Biomedical Sciences, University of Vermont, Burlington, Vermont, United States of America.
  • Tran F; School of Chemistry and Biomedical Sciences Research Complex, University of St Andrews and EaStCHEM, North Haugh, St Andrews, Fife, Scotland, United Kingdom.
  • Pathak RB; School of Chemistry and Biomedical Sciences Research Complex, University of St Andrews and EaStCHEM, North Haugh, St Andrews, Fife, Scotland, United Kingdom.
  • Poupart S; School of Chemistry and Biomedical Sciences Research Complex, University of St Andrews and EaStCHEM, North Haugh, St Andrews, Fife, Scotland, United Kingdom.
  • Heaslip AT; Department of Microbiology and Molecular Genetics, University of Vermont, Burlington, Vermont, United States of America.
  • Ballif BA; Department of Biology, University of Vermont, Burlington, Vermont, United States of America.
  • Westwood NJ; School of Chemistry and Biomedical Sciences Research Complex, University of St Andrews and EaStCHEM, North Haugh, St Andrews, Fife, Scotland, United Kingdom.
  • Ward GE; Department of Microbiology and Molecular Genetics, University of Vermont, Burlington, Vermont, United States of America.
PLoS One ; 9(6): e98056, 2014.
Article em En | MEDLINE | ID: mdl-24892871

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Parasitos / Piperidonas / Toxoplasma / Compostos de Benzilideno / Movimento Celular / Cadeias Leves de Miosina / Bibliotecas de Moléculas Pequenas / Antiparasitários Tipo de estudo: Diagnostic_studies Limite: Animals / Humans / Male Idioma: En Revista: PLoS One Assunto da revista: CIENCIA / MEDICINA Ano de publicação: 2014 Tipo de documento: Article País de afiliação: Estados Unidos País de publicação: Estados Unidos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Parasitos / Piperidonas / Toxoplasma / Compostos de Benzilideno / Movimento Celular / Cadeias Leves de Miosina / Bibliotecas de Moléculas Pequenas / Antiparasitários Tipo de estudo: Diagnostic_studies Limite: Animals / Humans / Male Idioma: En Revista: PLoS One Assunto da revista: CIENCIA / MEDICINA Ano de publicação: 2014 Tipo de documento: Article País de afiliação: Estados Unidos País de publicação: Estados Unidos