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Disabling Mitochondrial Peroxide Metabolism via Combinatorial Targeting of Peroxiredoxin 3 as an Effective Therapeutic Approach for Malignant Mesothelioma.
Cunniff, Brian; Newick, Kheng; Nelson, Kimberly J; Wozniak, Alexandra N; Beuschel, Stacie; Leavitt, Bruce; Bhave, Anant; Butnor, Kelly; Koenig, Andreas; Chouchani, Edward T; James, Andrew M; Haynes, Alexina C; Lowther, W Todd; Murphy, Michael P; Shukla, Arti; Heintz, Nicholas H.
Afiliação
  • Cunniff B; University of Vermont, College of Medicine, Department of Pathology, 149 Beaumont Ave, Burlington, VT, 05405, United States of America.
  • Newick K; University of Pennsylvania School of Medicine, Division of Pulmonary, Thoracic Oncology Research Laboratory, Philadelphia, PA, 19147, United States of America.
  • Nelson KJ; Wake Forest School of Medicine, Department of Biochemistry, Medical Center Boulevard, Winston-Salem, NC, 27157, United States of America.
  • Wozniak AN; University of Vermont, College of Medicine, Department of Pathology, 149 Beaumont Ave, Burlington, VT, 05405, United States of America.
  • Beuschel S; University of Vermont, College of Medicine, Department of Pathology, 149 Beaumont Ave, Burlington, VT, 05405, United States of America.
  • Leavitt B; University of Vermont, College of Medicine, Department of Surgery, 149 Beaumont Ave, Burlington, VT, 05405, United States of America.
  • Bhave A; University of Vermont, College of Medicine, Department of Radiology, 149 Beaumont Ave, Burlington, VT, 05405, United States of America.
  • Butnor K; University of Vermont, College of Medicine, Department of Pathology, 149 Beaumont Ave, Burlington, VT, 05405, United States of America.
  • Koenig A; University of Vermont, Department of Immunology medicine, 149 Beaumont Ave, Burlington, VT, 05405, United States of America.
  • Chouchani ET; Medical Research Council, Mitochondrial Biology Unit, Hills Road, Cambridge, CB2 0XY, United Kingdom; Department of Medicine, University of Cambridge, Addenbrooke's Hospital, Hills Road, Cambridge, CB2 2QQ, United Kingdom.
  • James AM; Medical Research Council, Mitochondrial Biology Unit, Hills Road, Cambridge, CB2 0XY, United Kingdom.
  • Haynes AC; Wake Forest School of Medicine, Department of Biochemistry, Medical Center Boulevard, Winston-Salem, NC, 27157, United States of America.
  • Lowther WT; Wake Forest School of Medicine, Department of Biochemistry, Medical Center Boulevard, Winston-Salem, NC, 27157, United States of America.
  • Murphy MP; Medical Research Council, Mitochondrial Biology Unit, Hills Road, Cambridge, CB2 0XY, United Kingdom.
  • Shukla A; University of Vermont, College of Medicine, Department of Pathology, 149 Beaumont Ave, Burlington, VT, 05405, United States of America.
  • Heintz NH; University of Vermont, College of Medicine, Department of Pathology, 149 Beaumont Ave, Burlington, VT, 05405, United States of America.
PLoS One ; 10(5): e0127310, 2015.
Article em En | MEDLINE | ID: mdl-26011724

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Peróxidos / Tioestreptona / Peroxirredoxina III / Neoplasias Pulmonares / Mesotelioma / Mitocôndrias Limite: Animals / Humans / Male Idioma: En Revista: PLoS One Assunto da revista: CIENCIA / MEDICINA Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Estados Unidos País de publicação: Estados Unidos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Peróxidos / Tioestreptona / Peroxirredoxina III / Neoplasias Pulmonares / Mesotelioma / Mitocôndrias Limite: Animals / Humans / Male Idioma: En Revista: PLoS One Assunto da revista: CIENCIA / MEDICINA Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Estados Unidos País de publicação: Estados Unidos