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Dual Exosite-binding Inhibitors of Insulin-degrading Enzyme Challenge Its Role as the Primary Mediator of Insulin Clearance in Vivo.
Durham, Timothy B; Toth, James L; Klimkowski, Valentine J; Cao, Julia X C; Siesky, Angela M; Alexander-Chacko, Jesline; Wu, Ginger Y; Dixon, Jeffrey T; McGee, James E; Wang, Yong; Guo, Sherry Y; Cavitt, Rachel Nicole; Schindler, John; Thibodeaux, Stefan J; Calvert, Nathan A; Coghlan, Michael J; Sindelar, Dana K; Christe, Michael; Kiselyov, Vladislav V; Michael, M Dodson; Sloop, Kyle W.
Afiliação
  • Durham TB; From the Discovery Chemistry Research and Technologies, durham_timothy_barrett@lilly.com.
  • Toth JL; From the Discovery Chemistry Research and Technologies.
  • Klimkowski VJ; From the Discovery Chemistry Research and Technologies.
  • Cao JX; Endocrine Discovery.
  • Siesky AM; Endocrine Discovery.
  • Alexander-Chacko J; Endocrine Discovery.
  • Wu GY; Endocrine Discovery.
  • Dixon JT; From the Discovery Chemistry Research and Technologies.
  • McGee JE; From the Discovery Chemistry Research and Technologies.
  • Wang Y; From the Discovery Chemistry Research and Technologies.
  • Guo SY; From the Discovery Chemistry Research and Technologies.
  • Cavitt RN; From the Discovery Chemistry Research and Technologies.
  • Schindler J; From the Discovery Chemistry Research and Technologies.
  • Thibodeaux SJ; Translational Science and Technologies, and.
  • Calvert NA; Drug Disposition, Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, Indiana 46285.
  • Coghlan MJ; From the Discovery Chemistry Research and Technologies.
  • Sindelar DK; Endocrine Discovery.
  • Christe M; Endocrine Discovery.
  • Kiselyov VV; Endocrine Discovery.
  • Michael MD; Endocrine Discovery.
  • Sloop KW; Endocrine Discovery.
J Biol Chem ; 290(33): 20044-59, 2015 Aug 14.
Article em En | MEDLINE | ID: mdl-26085101
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Inibidores Enzimáticos / Insulina / Insulisina Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: J Biol Chem Ano de publicação: 2015 Tipo de documento: Article País de publicação: Estados Unidos
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Inibidores Enzimáticos / Insulina / Insulisina Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: J Biol Chem Ano de publicação: 2015 Tipo de documento: Article País de publicação: Estados Unidos