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ELQ-300 prodrugs for enhanced delivery and single-dose cure of malaria.
Miley, Galen P; Pou, Sovitj; Winter, Rolf; Nilsen, Aaron; Li, Yuexin; Kelly, Jane X; Stickles, Allison M; Mather, Michael W; Forquer, Isaac P; Pershing, April M; White, Karen; Shackleford, David; Saunders, Jessica; Chen, Gong; Ting, Li-Min; Kim, Kami; Zakharov, Lev N; Donini, Cristina; Burrows, Jeremy N; Vaidya, Akhil B; Charman, Susan A; Riscoe, Michael K.
Afiliação
  • Miley GP; VA Medical Center, Experimental Chemotherapy Laboratory, Portland, Oregon, USA.
  • Pou S; VA Medical Center, Experimental Chemotherapy Laboratory, Portland, Oregon, USA.
  • Winter R; VA Medical Center, Experimental Chemotherapy Laboratory, Portland, Oregon, USA.
  • Nilsen A; VA Medical Center, Experimental Chemotherapy Laboratory, Portland, Oregon, USA.
  • Li Y; VA Medical Center, Experimental Chemotherapy Laboratory, Portland, Oregon, USA.
  • Kelly JX; VA Medical Center, Experimental Chemotherapy Laboratory, Portland, Oregon, USA.
  • Stickles AM; Oregon Health & Science University, Department of Molecular Microbiology and Immunology, Portland, Oregon, USA.
  • Mather MW; Drexel University College of Medicine, Department of Microbiology and Immunology, Philadelphia, Pennsylvania, USA.
  • Forquer IP; VA Medical Center, Experimental Chemotherapy Laboratory, Portland, Oregon, USA.
  • Pershing AM; Drexel University College of Medicine, Department of Microbiology and Immunology, Philadelphia, Pennsylvania, USA.
  • White K; Monash University, Centre for Drug Candidate Optimization, Parkville, Australia.
  • Shackleford D; Monash University, Centre for Drug Candidate Optimization, Parkville, Australia.
  • Saunders J; Monash University, Centre for Drug Candidate Optimization, Parkville, Australia.
  • Chen G; Monash University, Centre for Drug Candidate Optimization, Parkville, Australia.
  • Ting LM; Albert Einstein College of Medicine, Departments of Medicine, Pathology, and Microbiology and Immunology, Bronx, New York, USA.
  • Kim K; Albert Einstein College of Medicine, Departments of Medicine, Pathology, and Microbiology and Immunology, Bronx, New York, USA.
  • Zakharov LN; CAMCOR, University of Oregon, Eugene, Oregon, USA.
  • Donini C; Medicines for Malaria Venture, Geneva, Switzerland.
  • Burrows JN; Medicines for Malaria Venture, Geneva, Switzerland.
  • Vaidya AB; Drexel University College of Medicine, Department of Microbiology and Immunology, Philadelphia, Pennsylvania, USA Akhil.Vaidya@DrexelMed.edu Susan.Charman@monash.edu riscoem@ohsu.edu.
  • Charman SA; Monash University, Centre for Drug Candidate Optimization, Parkville, Australia Akhil.Vaidya@DrexelMed.edu Susan.Charman@monash.edu riscoem@ohsu.edu.
  • Riscoe MK; VA Medical Center, Experimental Chemotherapy Laboratory, Portland, Oregon, USA Oregon Health & Science University, Department of Molecular Microbiology and Immunology, Portland, Oregon, USA Akhil.Vaidya@DrexelMed.edu Susan.Charman@monash.edu riscoem@ohsu.edu.
Antimicrob Agents Chemother ; 59(9): 5555-60, 2015 Sep.
Article em En | MEDLINE | ID: mdl-26124159

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pró-Fármacos / Quinolonas / Malária / Antimaláricos Limite: Animals Idioma: En Revista: Antimicrob Agents Chemother Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Estados Unidos País de publicação: Estados Unidos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pró-Fármacos / Quinolonas / Malária / Antimaláricos Limite: Animals Idioma: En Revista: Antimicrob Agents Chemother Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Estados Unidos País de publicação: Estados Unidos