Drug-induced skin toxicity and clinical nursing of VitK cream on colorectal cancer patients.
Pak J Pharm Sci
; 28(4 Suppl): 1499-503, 2015 Jul.
Article
em En
| MEDLINE
| ID: mdl-26431649
ABSTRACT
To discuss the impact of 0.1% vitamin K1 (VitK1) cream on cetuximab-induced skin toxicity for colorectal cancer patients. 60 colorectal cancer patients with cetuximab therapy after hospitalization, were divided into experimental group (Ward A) and control group (Ward B) according to personnel sequential number, with 30 cases in each group. Routine nursing was implemented on control group. For experimental group, on the routine nursing basis, 0.1% VitK1 cream was smeared on face, neck, chest, back and nail (toenail) edge with three times one day at the application of cetuximab day. After cetuximab applied in 8 weeks, both skin itch and dry skin for patients in experimental group were significantly improved compared those in control group, showing statistically significant difference (W=708.000, P=0.001 W=662. 500, P=0.000). 0.1% VitK1 cream was conducive to improve both skin itch and dry skin symptoms in the cetuximab-induced skin toxicity for colorectal cancer patients.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Vitamina K 1
/
Pele
/
Dermatopatias
/
Neoplasias Colorretais
/
Anticorpos Monoclonais Humanizados
/
Antineoplásicos
Limite:
Adult
/
Aged
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
En
Revista:
Pak J Pharm Sci
Assunto da revista:
FARMACIA
/
FARMACOLOGIA
/
QUIMICA
Ano de publicação:
2015
Tipo de documento:
Article
País de afiliação:
China
País de publicação:
PAKISTAN
/
PAQUISTÃO
/
PK