Effects of the small molecule SIRT1 activator, SRT2104 on arterial stiffness in otherwise healthy cigarette smokers and subjects with type 2 diabetes mellitus.

Venkatasubramanian, Sowmya; Noh, Radzi M; Daga, Shruti; Langrish, Jeremy P; Mills, Nicholas L; Waterhouse, Brian R; Hoffmann, Ethan; Jacobson, Eric W; Lang, Ninian N; Frier, Brian M; Newby, David E

Venkatasubramanian, Sowmya; Noh, Radzi M; Daga, Shruti; Langrish, Jeremy P; Mills, Nicholas L; Waterhouse, Brian R; Hoffmann, Ethan; Jacobson, Eric W; Lang, Ninian N; Frier, Brian M; Newby, David E.

Afiliação

Venkatasubramanian S; Centre for Cardiovascular Science, University of Edinburgh , Edinburgh , UK.
Noh RM; Department of Diabetes , Royal Infirmary , Edinburgh , UK.
Daga S; GlaxoSmithKline , London , UK.
Langrish JP; Centre for Cardiovascular Science, University of Edinburgh , Edinburgh , UK.
Mills NL; Centre for Cardiovascular Science, University of Edinburgh , Edinburgh , UK.
Waterhouse BR; GlaxoSmithKline , Philadelphia, Pennsylvania , USA.
Hoffmann E; Sirtris, a GSK Company , Cambridge, Massachusetts , USA.
Jacobson EW; Sirtris, a GSK Company , Cambridge, Massachusetts , USA.
Lang NN; Centre for Cardiovascular Science, University of Edinburgh , Edinburgh , UK.
Frier BM; Department of Diabetes , Royal Infirmary , Edinburgh , UK.
Newby DE; Centre for Cardiovascular Science, University of Edinburgh , Edinburgh , UK.

Open Heart ; 3(1): e000402, 2016.

Article em En | MEDLINE | ID: mdl-27239324

Palavras-chave

SIRT1; arterial stiffness; cigarette smokers; diabetes mellitus; pulse wave

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Clinical_trials Idioma: En Revista: Open Heart Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Reino Unido País de publicação: Reino Unido

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