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Prosaposin is a regulator of progranulin levels and oligomerization.
Nicholson, Alexandra M; Finch, NiCole A; Almeida, Marcio; Perkerson, Ralph B; van Blitterswijk, Marka; Wojtas, Aleksandra; Cenik, Basar; Rotondo, Sergio; Inskeep, Venette; Almasy, Laura; Dyer, Thomas; Peralta, Juan; Jun, Goo; Wood, Andrew R; Frayling, Timothy M; Fuchsberger, Christian; Fowler, Sharon; Teslovich, Tanya M; Manning, Alisa K; Kumar, Satish; Curran, Joanne; Lehman, Donna; Abecasis, Goncalo; Duggirala, Ravindranath; Pottier, Cyril; Zahir, Haaris A; Crook, Julia E; Karydas, Anna; Mitic, Laura; Sun, Ying; Dickson, Dennis W; Bu, Guojun; Herz, Joachim; Yu, Gang; Miller, Bruce L; Ferguson, Shawn; Petersen, Ronald C; Graff-Radford, Neill; Blangero, John; Rademakers, Rosa.
Afiliação
  • Nicholson AM; Department of Neuroscience, Mayo Clinic, Jacksonville, Florida 32224, USA.
  • Finch NA; Department of Neuroscience, Mayo Clinic, Jacksonville, Florida 32224, USA.
  • Almeida M; South Texas Diabetes and Obesity Institute, University of Texas Rio Grande Valley School of Medicine, Brownsville, Texas 78520, USA.
  • Perkerson RB; Department of Neuroscience, Mayo Clinic, Jacksonville, Florida 32224, USA.
  • van Blitterswijk M; Department of Neuroscience, Mayo Clinic, Jacksonville, Florida 32224, USA.
  • Wojtas A; Department of Neuroscience, Mayo Clinic, Jacksonville, Florida 32224, USA.
  • Cenik B; Department of Neuroscience, Molecular Genetics, and Psychiatry, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA.
  • Rotondo S; Department of Cell Biology and Program in Cellular Neuroscience, Neurodegeneration and Repair, Yale University School of Medicine, New Haven, Connecticut 06510, USA.
  • Inskeep V; Division of Human Genetics, Cincinnati Children's Hospital Research Foundation, Cincinnati, Ohio 45229, USA.
  • Almasy L; South Texas Diabetes and Obesity Institute, University of Texas Rio Grande Valley School of Medicine, Brownsville, Texas 78520, USA.
  • Dyer T; South Texas Diabetes and Obesity Institute, University of Texas Rio Grande Valley School of Medicine, Brownsville, Texas 78520, USA.
  • Peralta J; South Texas Diabetes and Obesity Institute, University of Texas Rio Grande Valley School of Medicine, Brownsville, Texas 78520, USA.
  • Jun G; Human Genetics Center, School of Public Health, University of Texas Health Science Center at Houston, Houston, Texas 77030, USA.
  • Wood AR; Genetics of Complex Traits, St Luke's Campus, University of Exeter Medical School, University of Exeter, Exeter EX1 2LU, UK.
  • Frayling TM; Genetics of Complex Traits, St Luke's Campus, University of Exeter Medical School, University of Exeter, Exeter EX1 2LU, UK.
  • Fuchsberger C; Department of Biostatistics, Center for Statistical Genetics, University of Michigan, Ann Arbor, Michigan 48109, USA.
  • Fowler S; Department of Medicine, University of Texas Health Science Center, San Antonio, Texas 78229, USA.
  • Teslovich TM; Department of Biostatistics, Center for Statistical Genetics, University of Michigan, Ann Arbor, Michigan 48109, USA.
  • Manning AK; Center for Human Genetics Research, Massachusetts General Hospital, Boston, Massachusetts 02114, USA.
  • Kumar S; South Texas Diabetes and Obesity Institute, University of Texas Rio Grande Valley School of Medicine, Brownsville, Texas 78520, USA.
  • Curran J; South Texas Diabetes and Obesity Institute, University of Texas Rio Grande Valley School of Medicine, Brownsville, Texas 78520, USA.
  • Lehman D; Department of Medicine/Cardiology and Cellular &Structural Biology, University of Texas Health Science Center at San Antonio, San Antonio, Texas 78229, USA.
  • Abecasis G; Department of Biostatistics, Center for Statistical Genetics, University of Michigan, Ann Arbor, Michigan 48109, USA.
  • Duggirala R; South Texas Diabetes and Obesity Institute, University of Texas Rio Grande Valley School of Medicine, Brownsville, Texas 78520, USA.
  • Pottier C; Department of Neuroscience, Mayo Clinic, Jacksonville, Florida 32224, USA.
  • Zahir HA; Department of Neuroscience, Mayo Clinic, Jacksonville, Florida 32224, USA.
  • Crook JE; Department of Neuroscience, Mayo Clinic, Jacksonville, Florida 32224, USA.
  • Karydas A; Memory and Aging Center, Department of Neurology, University of California, San Francisco, California 94143, USA.
  • Mitic L; Memory and Aging Center, Department of Neurology, University of California, San Francisco, California 94143, USA.
  • Sun Y; Division of Human Genetics, Cincinnati Children's Hospital Research Foundation, Cincinnati, Ohio 45229, USA.
  • Dickson DW; Department of Neuroscience, Mayo Clinic, Jacksonville, Florida 32224, USA.
  • Bu G; Department of Neuroscience, Mayo Clinic, Jacksonville, Florida 32224, USA.
  • Herz J; Department of Molecular Genetics, Neuroscience, Neurology and Neurotherapeutics, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA.
  • Yu G; Department of Molecular Genetics, Neuroscience, Neurology and Neurotherapeutics, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA.
  • Miller BL; Memory and Aging Center, Department of Neurology, University of California, San Francisco, California 94143, USA.
  • Ferguson S; Department of Cell Biology and Program in Cellular Neuroscience, Neurodegeneration and Repair, Yale University School of Medicine, New Haven, Connecticut 06510, USA.
  • Petersen RC; Department of Neurology, Mayo Clinic, Rochester, Minnesota 55902, USA.
  • Graff-Radford N; Department of Neurology, Mayo Clinic, Jacksonville, Florida 32224, USA.
  • Blangero J; South Texas Diabetes and Obesity Institute, University of Texas Rio Grande Valley School of Medicine, Brownsville, Texas 78520, USA.
  • Rademakers R; Department of Neuroscience, Mayo Clinic, Jacksonville, Florida 32224, USA.
Nat Commun ; 7: 11992, 2016 06 30.
Article em En | MEDLINE | ID: mdl-27356620
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Peptídeos e Proteínas de Sinalização Intercelular / Saposinas / Demência Frontotemporal Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Nat Commun Assunto da revista: BIOLOGIA / CIENCIA Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Estados Unidos País de publicação: Reino Unido
Texto completo
Adicionar na Minha BVS
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Peptídeos e Proteínas de Sinalização Intercelular / Saposinas / Demência Frontotemporal Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Nat Commun Assunto da revista: BIOLOGIA / CIENCIA Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Estados Unidos País de publicação: Reino Unido