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Forced chromatin looping raises fetal hemoglobin in adult sickle cells to higher levels than pharmacologic inducers.
Breda, Laura; Motta, Irene; Lourenco, Silvia; Gemmo, Chiara; Deng, Wulan; Rupon, Jeremy W; Abdulmalik, Osheiza Y; Manwani, Deepa; Blobel, Gerd A; Rivella, Stefano.
Afiliação
  • Breda L; Department of Pediatrics, Division of Hematology-Oncology, Children's Blood and Cancer Foundation Laboratories, Weill Cornell Medical College, New York, NY; Department of Pediatrics, Division of Hematology, Children's Hospital of Philadelphia, Philadelphia, PA;
  • Motta I; Department of Pediatrics, Division of Hematology-Oncology, Children's Blood and Cancer Foundation Laboratories, Weill Cornell Medical College, New York, NY; Department of Clinical Science and Community Health, University of Milan, Milan, Italy;
  • Lourenco S; Department of Pediatrics, Division of Hematology-Oncology, Children's Blood and Cancer Foundation Laboratories, Weill Cornell Medical College, New York, NY; Department of Pediatrics, Division of Hematology, Children's Hospital of Philadelphia, Philadelphia, PA;
  • Gemmo C; Department of Pediatrics, Division of Hematology-Oncology, Children's Blood and Cancer Foundation Laboratories, Weill Cornell Medical College, New York, NY;
  • Deng W; Transcription Imaging Consortium, Janelia Research Campus, Howard Hughes Medical Institute, Ashburn, VA; and.
  • Rupon JW; Department of Pediatrics, Division of Hematology, Children's Hospital of Philadelphia, Philadelphia, PA;
  • Abdulmalik OY; Department of Pediatrics, Division of Hematology, Children's Hospital of Philadelphia, Philadelphia, PA;
  • Manwani D; Department of Pediatrics, Albert Einstein College of Medicine, Children's Hospital at Montefiore, Bronx, NY.
  • Blobel GA; Department of Pediatrics, Division of Hematology, Children's Hospital of Philadelphia, Philadelphia, PA;
  • Rivella S; Department of Pediatrics, Division of Hematology-Oncology, Children's Blood and Cancer Foundation Laboratories, Weill Cornell Medical College, New York, NY; Department of Pediatrics, Division of Hematology, Children's Hospital of Philadelphia, Philadelphia, PA;
Blood ; 128(8): 1139-43, 2016 08 25.
Article em En | MEDLINE | ID: mdl-27405777
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Hemoglobina Fetal / Cromatina / Anemia Falciforme Limite: Adult / Humans Idioma: En Revista: Blood Ano de publicação: 2016 Tipo de documento: Article País de publicação: Estados Unidos
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Hemoglobina Fetal / Cromatina / Anemia Falciforme Limite: Adult / Humans Idioma: En Revista: Blood Ano de publicação: 2016 Tipo de documento: Article País de publicação: Estados Unidos