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Risk factors for morbidities and mortality in children following pneumonectomy.
Respirology ; 22(1): 187-191, 2017 01.
Artigo em Inglês | MEDLINE | ID: mdl-27511212


Pneumonectomy (PNE) is a procedure infrequently performed in children. A high morbidity/mortality rate associated with PNE has been described. Few series have been published in the last 15 years. Risk factors associated with morbidity/mortality after PNE were evaluated. Indications, course, survival and complications of PNE in children were also analized.


In a case series of 51 children who underwent PNE, death within 30 days of surgery, pneumonia, empyema, sepsis, adult respiratory distress syndrome, bronchopleural fistula, bleeding, pneumothorax and post-PNE syndrome were considered major morbidities. Scoliosis, wound infection and atelectasis were considered minor morbidities.


Median age at PNE was 7.4 years; 45% were males. Indications of pneumonectomy were postinfectious bronchiectasis (61%), tumours (17%), pulmonary malformations (17%), aspiration syndrome (14%), cystic fibrosis (6%), immunodeficiency (4%) and trauma (2%). Mortality rate was 4% at 1 month. Major and minor morbidities were present in 23% and 27% of patients, respectively. Risk factors for development of morbidities after PNE were age ≤ 3 years (OR: 16.7; 95% CI: 2.4-117) and the need for mechanical ventilation for at least 4 days (OR: 8; 95% CI: 1.5-43.6).


Children are at high risk of death, major and minor morbidities following PNE. Caution is recommended for this group of patients.





Texto completo: Disponível Coleções: Bases de dados internacionais Base de dados: MEDLINE Assunto principal: Pneumonectomia / Pneumonia / Pneumotórax / Complicações Pós-Operatórias / Respiração Artificial / Sepse Aspecto clínico: Etiologia / Prognóstico Limite: Criança / Feminino / Humanos / Masculino País/Região como assunto: América do Sul / Argentina Idioma: Inglês Revista: Respirology Ano de publicação: 2017 Tipo de documento: Artigo País de afiliação: Argentina