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Inhibition of Notch pathway arrests PTEN-deficient advanced prostate cancer by triggering p27-driven cellular senescence.
Revandkar, Ajinkya; Perciato, Maria Luna; Toso, Alberto; Alajati, Abdullah; Chen, Jingjing; Gerber, Hermeto; Dimitrov, Mitko; Rinaldi, Andrea; Delaleu, Nicolas; Pasquini, Emiliano; D'Antuono, Rocco; Pinton, Sandra; Losa, Marco; Gnetti, Letizia; Arribas, Alberto; Fraering, Patrick; Bertoni, Francesco; Nepveu, Alain; Alimonti, Andrea.
Afiliação
  • Revandkar A; Institute of Oncology Research (IOR) and Oncology Institute of Southern Switzerland (IOSI), Bellinzona CH 6500, Switzerland.
  • Perciato ML; Faculty of Biology and Medicine, University of Lausanne (UNIL), Lausanne CH 1011, Switzerland.
  • Toso A; Institute of Oncology Research (IOR) and Oncology Institute of Southern Switzerland (IOSI), Bellinzona CH 6500, Switzerland.
  • Alajati A; Institute of Oncology Research (IOR) and Oncology Institute of Southern Switzerland (IOSI), Bellinzona CH 6500, Switzerland.
  • Chen J; Institute of Oncology Research (IOR) and Oncology Institute of Southern Switzerland (IOSI), Bellinzona CH 6500, Switzerland.
  • Gerber H; Institute of Oncology Research (IOR) and Oncology Institute of Southern Switzerland (IOSI), Bellinzona CH 6500, Switzerland.
  • Dimitrov M; Faculty of Biology and Medicine, University of Lausanne (UNIL), Lausanne CH 1011, Switzerland.
  • Rinaldi A; Brain Mind Institute and School of Life Sciences, Ecole Polytechnique Fédérale de Lausanne (EPFL), Lausanne CH 1015, Switzerland.
  • Delaleu N; Foundation Eclosion, Plan-Les-Ouates CH 1228, Switzerland.
  • Pasquini E; Campus Biotech Innovation Park, Geneva CH 1202, Switzerland.
  • D'Antuono R; Brain Mind Institute and School of Life Sciences, Ecole Polytechnique Fédérale de Lausanne (EPFL), Lausanne CH 1015, Switzerland.
  • Pinton S; Institute of Oncology Research (IOR) and Oncology Institute of Southern Switzerland (IOSI), Bellinzona CH 6500, Switzerland.
  • Losa M; Broegelmann Research Laboratory, Department of Clinical Science, University of Bergen, Bergen 5021, Norway.
  • Gnetti L; Institute of Oncology Research (IOR) and Oncology Institute of Southern Switzerland (IOSI), Bellinzona CH 6500, Switzerland.
  • Arribas A; Institute for Research in Biomedicine, University of Italian Switzerland, Via Vincenzo Vela 6, Bellinzona 6500, Switzerland.
  • Fraering P; Institute of Oncology Research (IOR) and Oncology Institute of Southern Switzerland (IOSI), Bellinzona CH 6500, Switzerland.
  • Bertoni F; Institute of Oncology Research (IOR) and Oncology Institute of Southern Switzerland (IOSI), Bellinzona CH 6500, Switzerland.
  • Nepveu A; Pathology Unit, University Hospital of Parma, Parma 43126, Italy.
  • Alimonti A; Institute of Oncology Research (IOR) and Oncology Institute of Southern Switzerland (IOSI), Bellinzona CH 6500, Switzerland.
Nat Commun ; 7: 13719, 2016 12 12.
Article em En | MEDLINE | ID: mdl-27941799
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias da Próstata / PTEN Fosfo-Hidrolase / Receptores Notch Tipo de estudo: Prognostic_studies Limite: Animals / Humans / Male Idioma: En Revista: Nat Commun Assunto da revista: BIOLOGIA / CIENCIA Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Suíça País de publicação: Reino Unido
Texto completo
Adicionar na Minha BVS
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XML
PubMed Links
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias da Próstata / PTEN Fosfo-Hidrolase / Receptores Notch Tipo de estudo: Prognostic_studies Limite: Animals / Humans / Male Idioma: En Revista: Nat Commun Assunto da revista: BIOLOGIA / CIENCIA Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Suíça País de publicação: Reino Unido