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Alternative RNA Processing of Topoisomerase IIα in Etoposide-Resistant Human Leukemia K562 Cells: Intron Retention Results in a Novel C-Terminal Truncated 90-kDa Isoform.
Kanagasabai, Ragu; Serdar, Lucas; Karmahapatra, Soumendrakrishna; Kientz, Corey A; Ellis, Justin; Ritke, Mary K; Elton, Terry S; Yalowich, Jack C.
Afiliação
  • Kanagasabai R; Division of Pharmacology, College of Pharmacy, The Ohio State University, Columbus, Ohio (R.K., L.S., S.K., C.A.K., J.E., T.S.E., J.C.Y.); James Comprehensive Cancer Center, The Ohio State University, Columbus, Ohio (J.C.Y.); and Department of Biology, University of Indianapolis, Indianapolis, India
  • Serdar L; Division of Pharmacology, College of Pharmacy, The Ohio State University, Columbus, Ohio (R.K., L.S., S.K., C.A.K., J.E., T.S.E., J.C.Y.); James Comprehensive Cancer Center, The Ohio State University, Columbus, Ohio (J.C.Y.); and Department of Biology, University of Indianapolis, Indianapolis, India
  • Karmahapatra S; Division of Pharmacology, College of Pharmacy, The Ohio State University, Columbus, Ohio (R.K., L.S., S.K., C.A.K., J.E., T.S.E., J.C.Y.); James Comprehensive Cancer Center, The Ohio State University, Columbus, Ohio (J.C.Y.); and Department of Biology, University of Indianapolis, Indianapolis, India
  • Kientz CA; Division of Pharmacology, College of Pharmacy, The Ohio State University, Columbus, Ohio (R.K., L.S., S.K., C.A.K., J.E., T.S.E., J.C.Y.); James Comprehensive Cancer Center, The Ohio State University, Columbus, Ohio (J.C.Y.); and Department of Biology, University of Indianapolis, Indianapolis, India
  • Ellis J; Division of Pharmacology, College of Pharmacy, The Ohio State University, Columbus, Ohio (R.K., L.S., S.K., C.A.K., J.E., T.S.E., J.C.Y.); James Comprehensive Cancer Center, The Ohio State University, Columbus, Ohio (J.C.Y.); and Department of Biology, University of Indianapolis, Indianapolis, India
  • Ritke MK; Division of Pharmacology, College of Pharmacy, The Ohio State University, Columbus, Ohio (R.K., L.S., S.K., C.A.K., J.E., T.S.E., J.C.Y.); James Comprehensive Cancer Center, The Ohio State University, Columbus, Ohio (J.C.Y.); and Department of Biology, University of Indianapolis, Indianapolis, India
  • Elton TS; Division of Pharmacology, College of Pharmacy, The Ohio State University, Columbus, Ohio (R.K., L.S., S.K., C.A.K., J.E., T.S.E., J.C.Y.); James Comprehensive Cancer Center, The Ohio State University, Columbus, Ohio (J.C.Y.); and Department of Biology, University of Indianapolis, Indianapolis, India
  • Yalowich JC; Division of Pharmacology, College of Pharmacy, The Ohio State University, Columbus, Ohio (R.K., L.S., S.K., C.A.K., J.E., T.S.E., J.C.Y.); James Comprehensive Cancer Center, The Ohio State University, Columbus, Ohio (J.C.Y.); and Department of Biology, University of Indianapolis, Indianapolis, India
J Pharmacol Exp Ther ; 360(1): 152-163, 2017 Jan.
Article em En | MEDLINE | ID: mdl-27974648
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Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Íntrons / Processamento Pós-Transcricional do RNA / Deleção de Sequência / DNA Topoisomerases Tipo II / Resistencia a Medicamentos Antineoplásicos / Proteínas de Ligação a DNA / Etoposídeo / Antígenos de Neoplasias / Antineoplásicos Limite: Humans Idioma: En Revista: J Pharmacol Exp Ther Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Índia País de publicação: Estados Unidos
Buscar no Google
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Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Íntrons / Processamento Pós-Transcricional do RNA / Deleção de Sequência / DNA Topoisomerases Tipo II / Resistencia a Medicamentos Antineoplásicos / Proteínas de Ligação a DNA / Etoposídeo / Antígenos de Neoplasias / Antineoplásicos Limite: Humans Idioma: En Revista: J Pharmacol Exp Ther Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Índia País de publicação: Estados Unidos