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Relationship between LINC00341 expression and cancer prognosis.
Oncotarget ; 8(9): 15283-15293, 2017 Feb 28.
Artigo em Inglês | MEDLINE | ID: mdl-28146429
ABSTRACT
LINC00341 is a novel long intergenic non-protein coding RNA with unknown functions. In our report, we investigated LINC00341 expression and its prognostic value in cancer patients. DNA over-methylation triggered low expression of LINC00341 and that was associated with poor prognosis in cancers. A meta-analysis further confirmed that high expression of LINC00341 was associated with a better prognosis in cancer patients. Both gene set enrichment analysis and meta-analysis showed that LINC00341 inhibited cancer metastasis. Finally, a large-scale multicentre analysis supported a prognostic value of LINC00341 in cancers.
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Texto completo: Disponível Coleções: Bases de dados internacionais Base de dados: MEDLINE Assunto principal: Neoplasias da Mama / Regulação Neoplásica da Expressão Gênica / Metilação de DNA / RNA Longo não Codificante Aspecto clínico: Prognóstico Limite: Humanos Idioma: Inglês Revista: Oncotarget Ano de publicação: 2017 Tipo de documento: Artigo