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The Asthma Mobile Health Study, a large-scale clinical observational study using ResearchKit.
Chan, Yu-Feng Yvonne; Wang, Pei; Rogers, Linda; Tignor, Nicole; Zweig, Micol; Hershman, Steven G; Genes, Nicholas; Scott, Erick R; Krock, Eric; Badgeley, Marcus; Edgar, Ron; Violante, Samantha; Wright, Rosalind; Powell, Charles A; Dudley, Joel T; Schadt, Eric E.
Afiliação
  • Chan YY; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
  • Wang P; Department of Emergency Medicine, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
  • Rogers L; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
  • Tignor N; Department of Medicine, Pulmonary, Critical Care and Sleep Medicine, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
  • Zweig M; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
  • Hershman SG; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
  • Genes N; LifeMap Solutions, Inc., New York, New York, USA.
  • Scott ER; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
  • Krock E; Department of Emergency Medicine, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
  • Badgeley M; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
  • Edgar R; LifeMap Solutions, Inc., New York, New York, USA.
  • Violante S; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
  • Wright R; LifeMap Solutions, Inc., New York, New York, USA.
  • Powell CA; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
  • Dudley JT; Department of Medicine, Pulmonary, Critical Care and Sleep Medicine, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
  • Schadt EE; Department of Pediatrics, Pulmonary and Critical Care, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
Nat Biotechnol ; 35(4): 354-362, 2017 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-28288104
ABSTRACT
The feasibility of using mobile health applications to conduct observational clinical studies requires rigorous validation. Here, we report initial findings from the Asthma Mobile Health Study, a research study, including recruitment, consent, and enrollment, conducted entirely remotely by smartphone. We achieved secure bidirectional data flow between investigators and 7,593 participants from across the United States, including many with severe asthma. Our platform enabled prospective collection of longitudinal, multidimensional data (e.g., surveys, devices, geolocation, and air quality) in a subset of users over the 6-month study period. Consistent trending and correlation of interrelated variables support the quality of data obtained via this method. We detected increased reporting of asthma symptoms in regions affected by heat, pollen, and wildfires. Potential challenges with this technology include selection bias, low retention rates, reporting bias, and data security. These issues require attention to realize the full potential of mobile platforms in research and patient care.
Assuntos
Texto completo: Disponível Coleções: Bases de dados internacionais Base de dados: MEDLINE Assunto principal: Projetos de Pesquisa / Asma / Vigilância da População / Inquéritos Epidemiológicos / Telemedicina / Pesquisa sobre Serviços de Saúde Tipo de estudo: Guia de prática clínica / Estudo de prevalência / Estudo de rastreamento Limite: Adolescente / Adulto / Idoso / Feminino / Humanos / Masculino / Meia-Idade / Jovem adulto País/Região como assunto: América do Norte Idioma: Inglês Revista: Nat Biotechnol Assunto da revista: Biotecnologia Ano de publicação: 2017 Tipo de documento: Artigo País de afiliação: Estados Unidos

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Texto completo: Disponível Coleções: Bases de dados internacionais Base de dados: MEDLINE Assunto principal: Projetos de Pesquisa / Asma / Vigilância da População / Inquéritos Epidemiológicos / Telemedicina / Pesquisa sobre Serviços de Saúde Tipo de estudo: Guia de prática clínica / Estudo de prevalência / Estudo de rastreamento Limite: Adolescente / Adulto / Idoso / Feminino / Humanos / Masculino / Meia-Idade / Jovem adulto País/Região como assunto: América do Norte Idioma: Inglês Revista: Nat Biotechnol Assunto da revista: Biotecnologia Ano de publicação: 2017 Tipo de documento: Artigo País de afiliação: Estados Unidos
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