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Caracterización y factores de riesgo de dilatación aórtica en pacientes pediátricos con válvula aórtica bicúspide. / Caracterización y factores de riesgo de dilatación aórtica en pacientes pediátricos con válvula aórtica bicúspide. / Characterization and risk factors for aortic dilatation in pediatric patients with bicuspid aortic valve.
Med Clin (Barc) ; 149(9): 391-396, 2017 Nov 09.
Artigo em Inglês, Espanhol | MEDLINE | ID: mdl-28629660
ABSTRACT

INTRODUCTION AND OBJECTIVES:

Dilatation of the ascending aorta associated with bicuspid aortic valve is a major cause of morbidity and mortality in adults. The main objective was to recognize the aortic involvement in children, its characteristics and risk factors.

METHODS:

Aortic measures of all pediatric patients with bicuspid aortic valve followed in a tertiary pediatric hospital between 1997 and 2015 were retrospectively taken. Patients with syndromes associated with aortic dilatation were excluded (n=17).

RESULTS:

Two hundred and six patients were included, 67.9% males. The commonest opening pattern was horizontal: 137 (66.7%). Half of the patients (101) had a history of surgical aortic coarctation, 46 (22.3%) had≥moderate aortic valve stenosis and 13 (6%) had≥moderate aortic insufficiency. Mean follow-up time was 6.1 (4.9) years; diagnosis of aortic dilatation was made during the first year of follow-up. Progression of the dilatation of the ascending aorta was noted in 17.1%, and of the aortic root in 2.5%. More than one-third (80/206) had aortic dilatation (z-score>2). The ascending aorta was exclusively affected in 70/80 patients, with sparing of the aortic root. In the multivariate analysis, patients with dilatation of the ascending aorta were associated with absence of coarctation (P=.001) and vertical opening pattern (P=.007).

CONCLUSIONS:

Pediatric patients with bicuspid aortic valve warrant medical follow-up for the frequent association with valve impairment and/or dilatation of the ascending aorta.
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Texto completo: Disponível Coleções: Bases de dados internacionais Base de dados: MEDLINE Assunto principal: Aorta / Valva Aórtica / Doenças das Valvas Cardíacas Aspecto clínico: Etiologia / Prognóstico Limite: Criança, pré-escolar / Feminino / Humanos / Lactente / Masculino Idioma: Inglês / Espanhol Revista: Med Clin (Barc) Ano de publicação: 2017 Tipo de documento: Artigo