Your browser doesn't support javascript.
Combining albumin-bilirubin score with future liver remnant predicts post-hepatectomy liver failure in HBV-associated HCC patients.
Liver Int ; 38(3): 494-502, 2018 03.
Artigo em Inglês | MEDLINE | ID: mdl-28685924


Accurate assessment of liver functional reserve pre-operatively is vital for safe hepatic resection. The ALBI score is a new model for assessing liver function. This study aimed to evaluate the value of combining ALBI score with sFLR in predicting post-operative morbidity and PHLF in HCC patients who underwent hepatectomy.


Patients undergoing three-dimensional CT reconstruction prior to hepatectomy for HCC between January 2015 and January 2017 were enrolled. The values of the CP score, ALBI score and sFLR in predicting post-operative outcomes were evaluated.


A total of 229 HCC patients were enrolled; 24 (10.5%) experienced major complications and 21 (9.2%) developed PHLF. The incidence of major complications and PHLF increased with increasing ALBI grade. The ALBI grade classified patients with CP grade A into two subgroups with different incidences of PHLF (P=.029). sFLR and ALBI scores were identified as independent predictors of PHLF. The AUC values for the CP score, ALBI score, sFLR and sFLR×ALBI for predicting major complications were 0.600, 0.756, 0.660 and 0.790 respectively. The AUC values of the CP score, ALBI score, sFLR and sFLR×ALBI for predicting PHLF were 0.646, 0.738, 0.758 and 0.884 respectively.


The ALBI score showed superior predictive value of post-operative outcomes over CP score, and the combination of sFLR and ALBI score was identified as a stronger predictor of post-operative outcomes than the sFLR or ALBI score alone.





Texto completo: Disponível Coleções: Bases de dados internacionais Base de dados: MEDLINE Assunto principal: Falência Hepática / Carcinoma Hepatocelular / Hepatectomia / Hepatite B / Neoplasias Hepáticas Aspecto clínico: Etiologia / Predição / Prognóstico Limite: Adolescente / Adulto / Idoso / Feminino / Humanos / Masculino / Meia-Idade / Jovem adulto País/Região como assunto: Ásia Idioma: Inglês Revista: Liver Int Assunto da revista: Gastroenterologia Ano de publicação: 2018 Tipo de documento: Artigo País de afiliação: China