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18F-FDG PET/MRI in Chronic Sciatica: Early Results Revealing Spinal and Nonspinal Abnormalities.
J Nucl Med ; 59(6): 967-972, 2018 06.
Artigo em Inglês | MEDLINE | ID: mdl-29097408
ABSTRACT
Chronic sciatica is a major cause of disability worldwide, but accurate diagnosis of the causative pathology remains challenging. In this report, the feasibility of an 18F-FDG PET/MRI approach for improved diagnosis of chronic sciatica is presented.

Methods:

18F-FDG PET/MRI was performed on 9 chronic sciatica patients and 5 healthy volunteers (healthy controls). Region-of-interest analysis using SUVmax was performed, and 18F-FDG uptake in lesions was compared with that in the corresponding areas in healthy controls.

Results:

Significantly increased 18F-FDG uptake was observed in detected lesions in all patients and was correlated with pain symptoms. 18F-FDG-avid lesions not only were found in impinged spinal nerves but also were associated with nonspinal causes of pain, such as facet joint degeneration, pars defect, or presumed scar neuroma.

Conclusion:

The feasibility of 18F-FDG PET/MRI for diagnosing pain generators in chronic sciatica was demonstrated, revealing various possible etiologies.
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Texto completo: Disponível Coleções: Bases de dados internacionais Base de dados: MEDLINE Assunto principal: Ciática / Coluna Vertebral / Imagem por Ressonância Magnética / Fluordesoxiglucose F18 / Tomografia por Emissão de Pósitrons / Imagem Multimodal Limite: Adulto / Feminino / Humanos / Masculino / Meia-Idade / Jovem adulto Idioma: Inglês Revista: J Nucl Med Ano de publicação: 2018 Tipo de documento: Artigo