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Chemical Constituents from Euphorbia kansui.
Molecules ; 22(12)2017 Dec 08.
Artigo em Inglês | MEDLINE | ID: mdl-29292735
ABSTRACT
In this research, a new triterpenoid, tirucalla-8,24-diene-3ß,11ß-diol-7-one (1), and eupha-8,24-diene-3ß,11ß-diol-7-one (2), which was isolated from Euphorbia kansui for the first time, together with twelve other known compounds (3-14), were isolated from the ethyl acetate extract of Euphorbia kansui. Their structures were elucidated based on High resolution electrospray ionization mass spectrometry (HR-ESI-MS), Infrared Spectroscopy (IR), 1D and 2D Nuclear Magnetic Resonance (NMR) data. Both constituents 1 and 2 exhibited moderate cytotoxicity against colon cancer HCT-116, gastric cancer MKN-45 and breast cancer MCF-7.
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Texto completo: Disponível Coleções: Bases de dados internacionais Base de dados: MEDLINE Assunto principal: Triterpenos / Extratos Vegetais / Euphorbia / Antineoplásicos Fitogênicos Limite: Humanos Idioma: Inglês Assunto da revista: Biologia Ano de publicação: 2017 Tipo de documento: Artigo