Your browser doesn't support javascript.
loading
The intracranial pressure curve correlates to the pulsatile component of cerebral blood flow.
Unnerbäck, Mårten; Bloomfield, Eric L; Söderström, Sven; Reinstrup, Peter.
Afiliação
  • Unnerbäck M; Department of Clinical Sciences Lund, Intensive Care and Perioperative Medicine, Lund University, Skane University Hospital, Malmö, Sweden. Marten.Unnerback@skane.se.
  • Bloomfield EL; IPV SUS Malmö, Inga Marie Nilssons gata 47, 205 02, Malmö, Sweden. Marten.Unnerback@skane.se.
  • Söderström S; Department of Anesthesiology/CCM, Mayo Clinic, Rochester, MN, USA.
  • Reinstrup P; Department of Clinical Sciences Lund, Neurosurgery, Lund University, Skane University Hospital, Lund, Sweden.
J Clin Monit Comput ; 33(1): 77-83, 2019 Feb.
Article em En | MEDLINE | ID: mdl-29549499
ABSTRACT
Current methods to measure cerebral blood flow (CBF) in the neuro critical care setting cannot monitor the CBF continuously. In contrast, continuous measurement of intracranial pressure (ICP) is readily accomplished, and there is a component of ICP that correlates with arterial inflow of blood into the cranial cavity. This property may have utility in using continuous ICP curve analysis to continuously estimate CBF. We examined the data from 13 patients, monitored with an intraventricular ICP device determining the pulsatile amplitude ICPamp as well as the area under the ICP curve (AUCICP). Using an elastance measurement, the ICP curve was converted to craniospinal volume (AUCΔV). The patients were examined with Phase Contrast Magnetic Resonance Imaging (MRI), measuring flow in the carotid and vertebral arteries. This made it possible to calculate CBF for one cardiac cycle (ccCBFMRtot) and divide it into the pulsatile (ccCBFMRpuls) and non-pulsatile (ccCBFMRconst) flow. ICP derived data and MRI measurements were compared. Linear regression was used to establish wellness of fit and ANOVA was used to calculate the P value. No correlation was found between ICPamp and the ccICPMRpuls (P = 0.067). In contrast there was a correlation between the AUCICP and ccCBFMRpuls (R2 = 0.440 P = 0.013). The AUCΔV correlated more appropriately with the ccCBFMRpuls. (R2 = 0.688 P < 0.001). Our findings suggests that the pulsatile part of the intracranial pressure curve, especially when transformed into a volume curve, correlates to the pulsatile part of the CBF.
Assuntos
Palavras-chave

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Processamento de Sinais Assistido por Computador / Pressão Intracraniana / Circulação Cerebrovascular / Monitorização Fisiológica Tipo de estudo: Prognostic_studies Limite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: J Clin Monit Comput Assunto da revista: INFORMATICA MEDICA / MEDICINA Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Suécia

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Processamento de Sinais Assistido por Computador / Pressão Intracraniana / Circulação Cerebrovascular / Monitorização Fisiológica Tipo de estudo: Prognostic_studies Limite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: J Clin Monit Comput Assunto da revista: INFORMATICA MEDICA / MEDICINA Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Suécia