Lipidomics reveal aryl hydrocarbon receptor (Ahr)-regulated lipid metabolic pathway in alpha-naphthyl isothiocyanate (ANIT)-induced intrahepatic cholestasis.

Wang, Bao-Long; Zhang, Chang-Wen; Wang, Liang; Tang, Kun-Long; Tanaka, Naoki; Gonzalez, Frank J; Xu, Yong; Fang, Zhong-Ze

Wang, Bao-Long; Zhang, Chang-Wen; Wang, Liang; Tang, Kun-Long; Tanaka, Naoki; Gonzalez, Frank J; Xu, Yong; Fang, Zhong-Ze.

Afiliação

Wang BL; a Department of Urology , The Second Hospital of Tianjin Medical University, Tianjin Institute of Urology , Tianjin , China.
Zhang CW; b Department of Urology , General Hospital of Tianjin Medical University , Tianjin , China.
Wang L; a Department of Urology , The Second Hospital of Tianjin Medical University, Tianjin Institute of Urology , Tianjin , China.
Tang KL; b Department of Urology , General Hospital of Tianjin Medical University , Tianjin , China.
Tanaka N; b Department of Urology , General Hospital of Tianjin Medical University , Tianjin , China.
Gonzalez FJ; c Laboratory of Metabolism , Center for Cancer Research, National Institutes of Health , Bethesda , MD , USA.
Xu Y; d Department of Metabolic Regulation , Shinshu University Graduate School of Medicine , Matsumoto , Japan.
Fang ZZ; c Laboratory of Metabolism , Center for Cancer Research, National Institutes of Health , Bethesda , MD , USA.

Xenobiotica ; 49(5): 591-601, 2019 May.

Article em En | MEDLINE | ID: mdl-29737914

Assuntos

1-Naftilisotiocianato/toxicidade; Colestase Intra-Hepática/induzido quimicamente; Colestase Intra-Hepática/metabolismo; Metabolismo dos Lipídeos/efeitos dos fármacos; Receptores de Hidrocarboneto Arílico/metabolismo; Animais; Colestase Intra-Hepática/genética; Colestase Intra-Hepática/patologia; Metabolismo dos Lipídeos/genética; Camundongos; Camundongos Knockout; Receptores de Hidrocarboneto Arílico/genética

Palavras-chave

Intrahepatic cholestasis; alpha-naphthyl isothiocyanate (ANIT); aryl hydrocarbon receptor (Ahr); lipidomics

Texto completo

Adicionar na Minha BVS

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Colestase Intra-Hepática / Receptores de Hidrocarboneto Arílico / Metabolismo dos Lipídeos / 1-Naftilisotiocianato Limite: Animals Idioma: En Revista: Xenobiotica Ano de publicação: 2019 Tipo de documento: Article País de afiliação: China País de publicação: Reino Unido

Texto completo

Adicionar na Minha BVS

Imprimir

XML

PubMed Links

Buscar no Google